WO3 Nanofiber-Based Biomarker Detectors Enabled by Protein-Encapsulated Catalyst Self-Assembled on Polystyrene Colloid Templates

Seon-Jin Choi, Sang Joon Kim, Hee Jin Cho, Ji Soo Jang, Yi Min Lin, Harry L. Tuller, Gregory C. Rutledge, Il Doo Kim

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

A novel catalyst functionalization method, based on protein-encapsulated metallic nanoparticles (NPs) and their self-assembly on polystyrene (PS) colloid templates, is used to form catalyst-loaded porous WO3 nanofibers (NFs). The metallic NPs, composed of Au, Pd, or Pt, are encapsulated within a protein cage, i.e., apoferritin, to form unagglomerated monodispersed particles with diameters of less than 5 nm. The catalytic NPs maintain their nanoscale size, even following high-temperature heat-treatment during synthesis, which is attributed to the discrete self-assembly of NPs on PS colloid templates. In addition, the PS templates generate open pores on the electrospun WO3 NFs, facilitating gas molecule transport into the sensing layers and promoting active surface reactions. As a result, the Au and Pd NP-loaded porous WO3 NFs show superior sensitivity toward hydrogen sulfide, as evidenced by responses (Rair/Rgas) of 11.1 and 43.5 at 350 °C, respectively. These responses represent 1.8- And 7.1-fold improvements compared to that of dense WO3 NFs (Rair/Rgas = 6.1). Moreover, Pt NP-loaded porous WO3 NFs exhibit high acetone sensitivity with response of 28.9. These results demonstrate a novel catalyst loading method, in which small NPs are well-dispersed within the pores of WO3 NFs, that is applicable to high sensitivity breath sensors.

Original languageEnglish
Pages (from-to)911-920
Number of pages10
JournalSmall
Volume12
Issue number7
DOIs
StatePublished - 2016 Feb 17

Fingerprint

Nanofibers
Polystyrenes
Colloids
Biomarkers
Nanoparticles
Detectors
Proteins
Catalysts
Metal Nanoparticles
Self assembly
Apoferritins
Hydrogen Sulfide
Acetone
Hydrogen sulfide
Surface reactions
Hot Temperature
Gases
Heat treatment
Temperature
Molecules

Keywords

  • chemiresistive sensors
  • nanofibers
  • polystyrene colloids
  • protein-encapsulated catalysts
  • self-assembly

Cite this

Choi, Seon-Jin ; Kim, Sang Joon ; Cho, Hee Jin ; Jang, Ji Soo ; Lin, Yi Min ; Tuller, Harry L. ; Rutledge, Gregory C. ; Kim, Il Doo. / WO3 Nanofiber-Based Biomarker Detectors Enabled by Protein-Encapsulated Catalyst Self-Assembled on Polystyrene Colloid Templates. In: Small. 2016 ; Vol. 12, No. 7. pp. 911-920.
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abstract = "A novel catalyst functionalization method, based on protein-encapsulated metallic nanoparticles (NPs) and their self-assembly on polystyrene (PS) colloid templates, is used to form catalyst-loaded porous WO3 nanofibers (NFs). The metallic NPs, composed of Au, Pd, or Pt, are encapsulated within a protein cage, i.e., apoferritin, to form unagglomerated monodispersed particles with diameters of less than 5 nm. The catalytic NPs maintain their nanoscale size, even following high-temperature heat-treatment during synthesis, which is attributed to the discrete self-assembly of NPs on PS colloid templates. In addition, the PS templates generate open pores on the electrospun WO3 NFs, facilitating gas molecule transport into the sensing layers and promoting active surface reactions. As a result, the Au and Pd NP-loaded porous WO3 NFs show superior sensitivity toward hydrogen sulfide, as evidenced by responses (Rair/Rgas) of 11.1 and 43.5 at 350 °C, respectively. These responses represent 1.8- And 7.1-fold improvements compared to that of dense WO3 NFs (Rair/Rgas = 6.1). Moreover, Pt NP-loaded porous WO3 NFs exhibit high acetone sensitivity with response of 28.9. These results demonstrate a novel catalyst loading method, in which small NPs are well-dispersed within the pores of WO3 NFs, that is applicable to high sensitivity breath sensors.",
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WO3 Nanofiber-Based Biomarker Detectors Enabled by Protein-Encapsulated Catalyst Self-Assembled on Polystyrene Colloid Templates. / Choi, Seon-Jin; Kim, Sang Joon; Cho, Hee Jin; Jang, Ji Soo; Lin, Yi Min; Tuller, Harry L.; Rutledge, Gregory C.; Kim, Il Doo.

In: Small, Vol. 12, No. 7, 17.02.2016, p. 911-920.

Research output: Contribution to journalArticle

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T1 - WO3 Nanofiber-Based Biomarker Detectors Enabled by Protein-Encapsulated Catalyst Self-Assembled on Polystyrene Colloid Templates

AU - Choi, Seon-Jin

AU - Kim, Sang Joon

AU - Cho, Hee Jin

AU - Jang, Ji Soo

AU - Lin, Yi Min

AU - Tuller, Harry L.

AU - Rutledge, Gregory C.

AU - Kim, Il Doo

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