Treatment outcomes and quality of life in oropharyngeal cancer after surgery-based versus radiation-based treatment

Tae Wook Kim, Hye Youn Youm, Hayoung Byun, Young Ik Son, Chung Hwan Baek

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Objectives. Advances in reconstruction and conservative surgery and the importance of quality of life (QOL) encouraged this reevaluation of surgery-based treatments for oropharyngeal cancer. We tried to compare treatment outcome and QOL after surgery-based versus radiation-based treatment in oropharyngeal cancer. Methods. The 133 eligible patients were divided into surgery-based and radiotherapy (RT)-based treatment groups. Medical records were reviewed, and EORTC QLQ-C30 and HN65 questionnaires were completed for survivors. Three-year overall survivals, disease-free survivals, locoregional control rates, and QOL scores were compared between the two groups. Results. Demographic data and overall stages were not significantly different between the two groups, and all survival rates were non-significantly different, either. The scores for most QOL items were equivalent, however, for a few items, scores were significantly better in surgery-based group. Conclusion. The surgery-based group achieved equivalent treatment outcomes and slightly better QOL scores than the RT-based group. The results of this study suggest that surgery could still be considered as a first-line therapy for oropharyngeal cancer.

Original languageEnglish
Pages (from-to)153-160
Number of pages8
JournalClinical and Experimental Otorhinolaryngology
Volume3
Issue number3
DOIs
StatePublished - 2010 Sep
Externally publishedYes

Keywords

  • Oropharyngeal cancer
  • Quality of life
  • Radiation
  • Surgery
  • Treatment outcome

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