Treatment and prevention of acute exacerbation of chronic obstructive pulmonary disease

Seong Yong Lim, Hyun Jung Kim, Seung Won Ra, Ji Hyun Lee, Tae-Hyung Kim

Research output: Contribution to journalArticle

Abstract

Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined as an acute aggravation of the patient’s respiratory symptoms, particularly cough, sputum production, and dyspnea, which requires a change of medication. COPD exacerbation leads to an accelerated decline in lung function, poorer health status, and is the main cause of hospital admission and death in patients with COPD. A majority of COPD exacerbations are triggered by respiratory infection. The Management of acute exacerbation of COPD consists of systemic corticosteroids, antibiotics, and inhaled short-acting bronchodilators. Oxygen supplementation is an essential component of treatment to improve hypoxemia. Noninvasive or invasive ventilator support is necessary for COPD patients with severe exacerbation, particularly associated with hypercapnic respiratory failure. The Korean clinical practice guideline for COPD was revised in 2018 by the members of the Korean Academy of Tuberculosis and Respiratory Diseases as well as participating members of the Health Insurance Review and Assessment Service. The purpose of this review is to provide an overview of the treatment and prevention strategies recommended in the 2018 Korean Academy of Tuberculosis and Respiratory Diseases for patient with acute exacerbation of COPD.

Original languageEnglish
Pages (from-to)552-556
Number of pages5
JournalJournal of the Korean Medical Association
Volume61
Issue number9
DOIs
StatePublished - 2018 Sep 1

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Chronic Obstructive Pulmonary Disease
Therapeutics
Disease Progression
Tuberculosis
Bronchodilator Agents
Mechanical Ventilators
Health Insurance
Sputum
Practice Guidelines
Cough
Respiratory Tract Infections
Respiratory Insufficiency
Dyspnea
Health Status
Adrenal Cortex Hormones
Oxygen
Anti-Bacterial Agents
Lung

Keywords

  • Acute exacerbation
  • Chronic obstructive
  • Prevention & control
  • Pulmonary disease
  • Therapeutics

Cite this

Lim, Seong Yong ; Kim, Hyun Jung ; Ra, Seung Won ; Lee, Ji Hyun ; Kim, Tae-Hyung. / Treatment and prevention of acute exacerbation of chronic obstructive pulmonary disease. In: Journal of the Korean Medical Association. 2018 ; Vol. 61, No. 9. pp. 552-556.
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Treatment and prevention of acute exacerbation of chronic obstructive pulmonary disease. / Lim, Seong Yong; Kim, Hyun Jung; Ra, Seung Won; Lee, Ji Hyun; Kim, Tae-Hyung.

In: Journal of the Korean Medical Association, Vol. 61, No. 9, 01.09.2018, p. 552-556.

Research output: Contribution to journalArticle

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