The effect of focused ultrasonic stimulation on the activity of hippocampal neurons in multi-channel electrode

Jeong Bong Choi, Sung Hwan Lim, Kyeong Won Cho, Do Hyoung Kim, Dong Pyo Jang, In Young Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Many experiments investigated the neuro modulatory effects of ultrasonic stimulation, yet there are few researches that investigate which parameters are needed to change activity of excitable cells. In this study, changes in neural network activities were recorded during ultrasonic stimulation with various parameters using a multi-electrode array (MEA). This study concludes, ultrasonic stimulation with intensity of 16.14 mW/cm2 induces change to the neuronal network activity. However, the timing of neuronal activity and stimulus was not synchronized. The mechanical stimuli may not have a direct effect on neuronal activities but somehow help neuronal cells to be in a more excitable state, although further study is necessary.

Original languageEnglish
Title of host publication2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
Pages731-734
Number of pages4
DOIs
Publication statusPublished - 2013 Dec 1
Event2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 - San Diego, CA, United States
Duration: 2013 Nov 62013 Nov 8

Publication series

NameInternational IEEE/EMBS Conference on Neural Engineering, NER
ISSN (Print)1948-3546
ISSN (Electronic)1948-3554

Other

Other2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013
CountryUnited States
CitySan Diego, CA
Period13/11/613/11/8

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Choi, J. B., Lim, S. H., Cho, K. W., Kim, D. H., Jang, D. P., & Kim, I. Y. (2013). The effect of focused ultrasonic stimulation on the activity of hippocampal neurons in multi-channel electrode. In 2013 6th International IEEE EMBS Conference on Neural Engineering, NER 2013 (pp. 731-734). [6696038] (International IEEE/EMBS Conference on Neural Engineering, NER). https://doi.org/10.1109/NER.2013.6696038