The effect of DNA on mechanical properties of nanofiber hydrogels

Min Kyoon Shin, Shi Hyeong Kim, Sung Il Jung, Sun I. Kim, Seon Jeong Kim, Byung Joo Kim, Insuk So

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Abstract

Uniform poly(vinyl alcohol) (PVA) nanofiber gels incorporating double-stranded deoxyribonucleic acid (DNA) were fabricated without the aid of cross-linkers employing electrospinning. Creep and tensile tests of the DNA/PVA nanofiber gels were carried out in an aqueous medium to analyze interactions between the DNA and PVA. The DNA/PVA gels had a higher elastic modulus than the PVA gel. The viscosity with increasing external load was calculated by applying the Burger model to the creep curves. We conclude that DNA is relatively weakly bound with the PVA chains, although the elastic modulus of the DNA/PVA gels was higher than that of PVA gel.

Original languageEnglish
Article number171903
JournalApplied Physics Letters
Volume93
Issue number17
DOIs
StatePublished - 2008 Nov 6

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    Shin, M. K., Kim, S. H., Jung, S. I., Kim, S. I., Kim, S. J., Kim, B. J., & So, I. (2008). The effect of DNA on mechanical properties of nanofiber hydrogels. Applied Physics Letters, 93(17), [171903]. https://doi.org/10.1063/1.3009204