Successful treatment with ultrasound-guided aspiration of intractable methicillin-resistant staphylococcus aureus brain abscess in an extremely low birth weight infant

Hyun Kyung Park, Young Soo Lee, Sung Hee Oh, Hyun Ju Lee

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Brain abscesses are an uncommon and devastating complication of bacteremia in extremely low birth weight infants (<1 kg). We report a 25-week preterm neonate who developed a brain abscess 4 weeks following methicillin-resistant Staphyloccocus aureus (MRSA) sepsis. A huge brain abscess was seen with routine brain sonography on day 19 of life. Despite intravenous vancomycin treatment, the brain abscess increased in size and was associated with increased intracranial pressure on day 49 of life. The brain abscess was accompanied by mild meningeal inflammation with negative blood and cerebrospinal fluid cultures. Diagnosis of abscess was confirmed by bedside ultrasound-guided aspiration, and MRSA was isolated from the pus culture. The MRSA brain abscess refractory to vancomycin was successfully treated by surgical ultrasound-guided percutaneous needle aspiration of brain abscess and prolonged courses of antibiotic administration. At the time of this report, the infant was 9 months old (corrected age was 6 months) and had normal neurodevelopment for her corrected age on the Bayley Infant Neurodevelopmental Screener.

Original languageEnglish
Pages (from-to)210-215
Number of pages6
JournalPediatric Neurosurgery
Volume50
Issue number4
DOIs
StatePublished - 2015 Aug 14

Fingerprint

Extremely Low Birth Weight Infant
Brain Abscess
Methicillin-Resistant Staphylococcus aureus
Methicillin Resistance
Vancomycin
Therapeutics
Suppuration
Intracranial Pressure
Bacteremia
Abscess
Needles
Cerebrospinal Fluid
Ultrasonography
Sepsis
Newborn Infant
Anti-Bacterial Agents
Inflammation
Brain

Keywords

  • Brain abscess
  • Development
  • Methicillin-resistant Staphylococcus aureus

Cite this

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abstract = "Brain abscesses are an uncommon and devastating complication of bacteremia in extremely low birth weight infants (<1 kg). We report a 25-week preterm neonate who developed a brain abscess 4 weeks following methicillin-resistant Staphyloccocus aureus (MRSA) sepsis. A huge brain abscess was seen with routine brain sonography on day 19 of life. Despite intravenous vancomycin treatment, the brain abscess increased in size and was associated with increased intracranial pressure on day 49 of life. The brain abscess was accompanied by mild meningeal inflammation with negative blood and cerebrospinal fluid cultures. Diagnosis of abscess was confirmed by bedside ultrasound-guided aspiration, and MRSA was isolated from the pus culture. The MRSA brain abscess refractory to vancomycin was successfully treated by surgical ultrasound-guided percutaneous needle aspiration of brain abscess and prolonged courses of antibiotic administration. At the time of this report, the infant was 9 months old (corrected age was 6 months) and had normal neurodevelopment for her corrected age on the Bayley Infant Neurodevelopmental Screener.",
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Successful treatment with ultrasound-guided aspiration of intractable methicillin-resistant staphylococcus aureus brain abscess in an extremely low birth weight infant. / Park, Hyun Kyung; Lee, Young Soo; Oh, Sung Hee; Lee, Hyun Ju.

In: Pediatric Neurosurgery, Vol. 50, No. 4, 14.08.2015, p. 210-215.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Oh, Sung Hee

AU - Lee, Hyun Ju

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AB - Brain abscesses are an uncommon and devastating complication of bacteremia in extremely low birth weight infants (<1 kg). We report a 25-week preterm neonate who developed a brain abscess 4 weeks following methicillin-resistant Staphyloccocus aureus (MRSA) sepsis. A huge brain abscess was seen with routine brain sonography on day 19 of life. Despite intravenous vancomycin treatment, the brain abscess increased in size and was associated with increased intracranial pressure on day 49 of life. The brain abscess was accompanied by mild meningeal inflammation with negative blood and cerebrospinal fluid cultures. Diagnosis of abscess was confirmed by bedside ultrasound-guided aspiration, and MRSA was isolated from the pus culture. The MRSA brain abscess refractory to vancomycin was successfully treated by surgical ultrasound-guided percutaneous needle aspiration of brain abscess and prolonged courses of antibiotic administration. At the time of this report, the infant was 9 months old (corrected age was 6 months) and had normal neurodevelopment for her corrected age on the Bayley Infant Neurodevelopmental Screener.

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