Spatiotemporally defined biomolecule preconcentrator by overlapping ion concentration polarization

Rhokyun Kwak, Ji Yoon Kang, Tae Song Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We demonstrate spatiotemporally defined preconcentrator by utilizing ion concentration polarization (ICP) between two identical cation exchange membranes (i.e. Nafion). When current flows through two membranes, which patterned on the bottom of the microchannel, ion depletion zone and ion enrichment zone can face each other on the anodic and cathodic sides of the membranes. If the membranes are close enough, two zones are merged and stabilized their location at all times (∼20 min), under any voltage applied (0.5-100V). This spatiotemporally defined ICP allows us to preconcentrate biomolecules up to 10,000-fold in 10min, with pinpointed the condensation position, i.e. between the Nafion membranes.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages269-271
Number of pages3
ISBN (Electronic)9780979806483
StatePublished - 2015 Jan 1
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 2015 Oct 252015 Oct 29

Publication series

NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period15/10/2515/10/29

Keywords

  • Ion concentration polarization
  • Ion exchange membrane
  • Preconcentration

Fingerprint Dive into the research topics of 'Spatiotemporally defined biomolecule preconcentrator by overlapping ion concentration polarization'. Together they form a unique fingerprint.

  • Cite this

    Kwak, R., Kang, J. Y., & Kim, T. S. (2015). Spatiotemporally defined biomolecule preconcentrator by overlapping ion concentration polarization. In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 269-271). (MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.