Simple synthetic route for hydroxyapatite colloidal nanoparticles via a Nd:YAG laser ablation in liquid medium

Sung Wook Mhin, Jeong Ho Ryu, Kang Min Kim, Gyeong Seon Park, Han Wool Ryu, Kwang Bo Shim, Takeshi Sasaki, Naoto Koshizaki

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Pulsed laser ablation (PLA) in liquid medium was successfully employed to synthesize hydroxyapatite (HAp) colloidal nanoparticles. The crystalline phase, particle morphology, size distribution and microstructure of the HAp nanoparticles were investigated in detail. The obtained HAp nanoparticles had spherical shape with sizes ranging from 5 to 20 nm. The laser ablation and the nanoparticle forming process were studied in terms of the explosive ejection mechanism by investigating the change of the surface morphology on target. The stoichiometry and bonding properties were studied by using XPS, FT-IR and Raman spectroscopy. A molar ratio of Ca/P of the prepared HAp nanoparticles was more stoichiometric than the value reported in the case of ablation in vacuum.

Original languageEnglish
Pages (from-to)435-440
Number of pages6
JournalApplied Physics A: Materials Science and Processing
Issue number2
StatePublished - 2009 Aug 1


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