Risk factors and clinical outcomes of delirium in osteoporotic hip fractures

Joon Yub Kim, Jeong Hyun Yoo, Eugene Kim, Ki Bum Kwon, Byeong Ryong Han, Yongun Cho, Jai Hyung Park

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: This study is performed to identify risk factors for delirium in osteoporotic hip fractures and to evaluate the hospitalization cost and clinical outcomes of delirium in osteoporotic hip. Methods: A total of 221 patients with osteoporotic hip fractures were assessed for eligibility between 2010 and 2014. Among them, 37 patients with delirium were allocated into the delirium group (group D) and 37 patients without delirium were allocated into the non-delirium group (group ND) by matching demographic factors. Risk factors such as time between admission and operation, body mass index, American Society of Anesthesiologists status, cognitive impairment, preoperative urinary catheter, electrolyte imbalance, preoperative hemoglobin, polymedication (medications > 5), pneumonia, anesthesia time, operation time, estimated blood loss, and total amount of transfusion were evaluated for correlation with incidence of delirium. The hospitalization cost was evaluated, and clinical outcomes such as readmission, mortality, and activity level at 1-year follow-up were evaluated. Results: In multivariate analysis, polymedication (p = 0.028) and preoperative indwelling urinary catheter insertion status (p = 0.007) were related to the incidence of delirium in patients with osteoporotic hip fractures. Group D showed a significantly higher hospitalization cost compared to group ND. However, delirium did not have a significant effect on length of hospital stay, readmission rate, postoperative 1-year mortality, and activity level. Conclusions: Polymedication and preoperative urinary catheter were related to perioperative delirium. In addition, delirium in osteoporotic hip fractures may not have a detrimental effect on clinical outcomes; however, hospitalization cost seemed to be increased due to delirium.

Original languageEnglish
JournalJournal of Orthopaedic Surgery
Volume25
Issue number3
DOIs
StatePublished - 2017 Jan 1

Fingerprint

Osteoporotic Fractures
Delirium
Hip Fractures
Urinary Catheters
Hospitalization
Costs and Cost Analysis
Length of Stay
Patient Readmission
Indwelling Catheters
Mortality
Incidence
Electrolytes
Hip
Pneumonia
Hemoglobins
Body Mass Index
Multivariate Analysis
Anesthesia
Demography

Keywords

  • Delirium
  • Matched-pair analysis
  • Osteoporotic fractures
  • Risk factors
  • Treatment outcome

Cite this

Kim, Joon Yub ; Yoo, Jeong Hyun ; Kim, Eugene ; Kwon, Ki Bum ; Han, Byeong Ryong ; Cho, Yongun ; Park, Jai Hyung. / Risk factors and clinical outcomes of delirium in osteoporotic hip fractures. In: Journal of Orthopaedic Surgery. 2017 ; Vol. 25, No. 3.
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abstract = "Purpose: This study is performed to identify risk factors for delirium in osteoporotic hip fractures and to evaluate the hospitalization cost and clinical outcomes of delirium in osteoporotic hip. Methods: A total of 221 patients with osteoporotic hip fractures were assessed for eligibility between 2010 and 2014. Among them, 37 patients with delirium were allocated into the delirium group (group D) and 37 patients without delirium were allocated into the non-delirium group (group ND) by matching demographic factors. Risk factors such as time between admission and operation, body mass index, American Society of Anesthesiologists status, cognitive impairment, preoperative urinary catheter, electrolyte imbalance, preoperative hemoglobin, polymedication (medications > 5), pneumonia, anesthesia time, operation time, estimated blood loss, and total amount of transfusion were evaluated for correlation with incidence of delirium. The hospitalization cost was evaluated, and clinical outcomes such as readmission, mortality, and activity level at 1-year follow-up were evaluated. Results: In multivariate analysis, polymedication (p = 0.028) and preoperative indwelling urinary catheter insertion status (p = 0.007) were related to the incidence of delirium in patients with osteoporotic hip fractures. Group D showed a significantly higher hospitalization cost compared to group ND. However, delirium did not have a significant effect on length of hospital stay, readmission rate, postoperative 1-year mortality, and activity level. Conclusions: Polymedication and preoperative urinary catheter were related to perioperative delirium. In addition, delirium in osteoporotic hip fractures may not have a detrimental effect on clinical outcomes; however, hospitalization cost seemed to be increased due to delirium.",
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Risk factors and clinical outcomes of delirium in osteoporotic hip fractures. / Kim, Joon Yub; Yoo, Jeong Hyun; Kim, Eugene; Kwon, Ki Bum; Han, Byeong Ryong; Cho, Yongun; Park, Jai Hyung.

In: Journal of Orthopaedic Surgery, Vol. 25, No. 3, 01.01.2017.

Research output: Contribution to journalArticle

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T1 - Risk factors and clinical outcomes of delirium in osteoporotic hip fractures

AU - Kim, Joon Yub

AU - Yoo, Jeong Hyun

AU - Kim, Eugene

AU - Kwon, Ki Bum

AU - Han, Byeong Ryong

AU - Cho, Yongun

AU - Park, Jai Hyung

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N2 - Purpose: This study is performed to identify risk factors for delirium in osteoporotic hip fractures and to evaluate the hospitalization cost and clinical outcomes of delirium in osteoporotic hip. Methods: A total of 221 patients with osteoporotic hip fractures were assessed for eligibility between 2010 and 2014. Among them, 37 patients with delirium were allocated into the delirium group (group D) and 37 patients without delirium were allocated into the non-delirium group (group ND) by matching demographic factors. Risk factors such as time between admission and operation, body mass index, American Society of Anesthesiologists status, cognitive impairment, preoperative urinary catheter, electrolyte imbalance, preoperative hemoglobin, polymedication (medications > 5), pneumonia, anesthesia time, operation time, estimated blood loss, and total amount of transfusion were evaluated for correlation with incidence of delirium. The hospitalization cost was evaluated, and clinical outcomes such as readmission, mortality, and activity level at 1-year follow-up were evaluated. Results: In multivariate analysis, polymedication (p = 0.028) and preoperative indwelling urinary catheter insertion status (p = 0.007) were related to the incidence of delirium in patients with osteoporotic hip fractures. Group D showed a significantly higher hospitalization cost compared to group ND. However, delirium did not have a significant effect on length of hospital stay, readmission rate, postoperative 1-year mortality, and activity level. Conclusions: Polymedication and preoperative urinary catheter were related to perioperative delirium. In addition, delirium in osteoporotic hip fractures may not have a detrimental effect on clinical outcomes; however, hospitalization cost seemed to be increased due to delirium.

AB - Purpose: This study is performed to identify risk factors for delirium in osteoporotic hip fractures and to evaluate the hospitalization cost and clinical outcomes of delirium in osteoporotic hip. Methods: A total of 221 patients with osteoporotic hip fractures were assessed for eligibility between 2010 and 2014. Among them, 37 patients with delirium were allocated into the delirium group (group D) and 37 patients without delirium were allocated into the non-delirium group (group ND) by matching demographic factors. Risk factors such as time between admission and operation, body mass index, American Society of Anesthesiologists status, cognitive impairment, preoperative urinary catheter, electrolyte imbalance, preoperative hemoglobin, polymedication (medications > 5), pneumonia, anesthesia time, operation time, estimated blood loss, and total amount of transfusion were evaluated for correlation with incidence of delirium. The hospitalization cost was evaluated, and clinical outcomes such as readmission, mortality, and activity level at 1-year follow-up were evaluated. Results: In multivariate analysis, polymedication (p = 0.028) and preoperative indwelling urinary catheter insertion status (p = 0.007) were related to the incidence of delirium in patients with osteoporotic hip fractures. Group D showed a significantly higher hospitalization cost compared to group ND. However, delirium did not have a significant effect on length of hospital stay, readmission rate, postoperative 1-year mortality, and activity level. Conclusions: Polymedication and preoperative urinary catheter were related to perioperative delirium. In addition, delirium in osteoporotic hip fractures may not have a detrimental effect on clinical outcomes; however, hospitalization cost seemed to be increased due to delirium.

KW - Delirium

KW - Matched-pair analysis

KW - Osteoporotic fractures

KW - Risk factors

KW - Treatment outcome

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