Promising bio-composites of polypyrrole and chitosan: Surface protective and in vitro biocompatibility performance on 316L SS implants

A. Madhan Kumar, Bharathi Suresh, Soumyadip Das, I. B. Obot, Akeem Yusuf Adesina, Ramakrishna Suresh

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Advanced biomedical materials can potentially be developed from combinations of natural biodegradable polymers and synthetic polymers. We synthesized bioactive composites based on polypyrrole/chitosan through in-situ electrochemical polymerization in oxalic acid medium. Surface characterization results revealed the influence of chitosan inclusion on polypyrrole (PPy) surface morphology. Contact angle results confirmed the enhancement in surface hydrophilicity due to the addition of chitosan into the PPy matrix. Electrochemical corrosion studies revealed that the composite coatings showed enhanced protective performance compared to pure PPy. Further, we investigated the effect of the composite coatings on the growth of MG-63 human osteoblast cells to assess their biocompatibility. Monte Carlo simulations were engaged to assess the interactions between the metal surface and composite coatings. The composite containing equal parts PPy and chitosan was found to be biocompatible; together with the corrosion protection results, the findings indicated that this bioactive coating material has potential for use in 316L SS implants.

Original languageEnglish
Pages (from-to)121-130
Number of pages10
JournalCarbohydrate Polymers
Volume173
DOIs
StatePublished - 2017 Oct 1

Fingerprint

Polypyrroles
Chitosan
Biocompatibility
Composite coatings
Composite materials
Natural polymers
Oxalic Acid
Electrochemical corrosion
Biodegradable polymers
Oxalic acid
Electropolymerization
Osteoblasts
Hydrophilicity
Corrosion protection
Contact angle
Surface morphology
Polymers
Metals
polypyrrole
Coatings

Keywords

  • Biocompatibility
  • Biomaterials
  • Chitosan
  • Coatings
  • Corrosion

Cite this

Kumar, A. Madhan ; Suresh, Bharathi ; Das, Soumyadip ; Obot, I. B. ; Adesina, Akeem Yusuf ; Suresh, Ramakrishna. / Promising bio-composites of polypyrrole and chitosan : Surface protective and in vitro biocompatibility performance on 316L SS implants. In: Carbohydrate Polymers. 2017 ; Vol. 173. pp. 121-130.
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Promising bio-composites of polypyrrole and chitosan : Surface protective and in vitro biocompatibility performance on 316L SS implants. / Kumar, A. Madhan; Suresh, Bharathi; Das, Soumyadip; Obot, I. B.; Adesina, Akeem Yusuf; Suresh, Ramakrishna.

In: Carbohydrate Polymers, Vol. 173, 01.10.2017, p. 121-130.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Promising bio-composites of polypyrrole and chitosan

T2 - Surface protective and in vitro biocompatibility performance on 316L SS implants

AU - Kumar, A. Madhan

AU - Suresh, Bharathi

AU - Das, Soumyadip

AU - Obot, I. B.

AU - Adesina, Akeem Yusuf

AU - Suresh, Ramakrishna

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AB - Advanced biomedical materials can potentially be developed from combinations of natural biodegradable polymers and synthetic polymers. We synthesized bioactive composites based on polypyrrole/chitosan through in-situ electrochemical polymerization in oxalic acid medium. Surface characterization results revealed the influence of chitosan inclusion on polypyrrole (PPy) surface morphology. Contact angle results confirmed the enhancement in surface hydrophilicity due to the addition of chitosan into the PPy matrix. Electrochemical corrosion studies revealed that the composite coatings showed enhanced protective performance compared to pure PPy. Further, we investigated the effect of the composite coatings on the growth of MG-63 human osteoblast cells to assess their biocompatibility. Monte Carlo simulations were engaged to assess the interactions between the metal surface and composite coatings. The composite containing equal parts PPy and chitosan was found to be biocompatible; together with the corrosion protection results, the findings indicated that this bioactive coating material has potential for use in 316L SS implants.

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KW - Biomaterials

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