Primary synovial sarcoma of the thyroid gland

Ki Seok Jang, Kyueng Whan Min, Si Hyong Jang, Sam Paik Seung, Kyung Tae, Jin Jang Se, Hyang Park Moon

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Synovial sarcoma is a rare but distinct soft tissue neoplasm, most commonly occurring in para-articular regions of the extremities of young adults and also occurring in the head and neck region. To the best of our knowledge, only one case of primary synovial sarcoma of the thyroid has been previously reported. Here, we report a 15-yr-old man who had a chief complaint of a palpable neck mass. The neck computed tomography revealed a relatively well-demarcated solid mass in the left thyroid gland. After fine needle aspiration cytology, total thyroidectomy and lymph node dissection were performed. Grossly, the mass was covered by the same capsule as the thyroid gland, measuring 6 x 5 x 5 cm in dimensions and weighing 78 gm. The cut surface showed a well demarcated, lobulated, grayish tan, and rubbery solid tumor. Histologically, this tumor was a biphasic synovial sarcoma. Immunohistochemical, ultrastructural, genetic studies, and cytologic findings were all consistent with synovial sarcoma. When synovial sarcomas arise in this unusual site, recognition and differential diagnosis become more difficult. The differential diagnosis of a spindle epithelial tumor with thymus-like differentiation is very difficult due to their similar clinical, histological, and immunohistochemical features. Ultrastructural and cytogenetic studies for synovial sarcoma are necessary to establish a definitive diagnosis.

Original languageEnglish
Pages (from-to)S154-S158
JournalJournal of Korean Medical Science
Volume22
Issue numberSUPPL.
StatePublished - 2007 Sep 1

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Synovial Sarcoma
Thyroid Gland
Neck
Differential Diagnosis
Soft Tissue Neoplasms
Thyroidectomy
Fine Needle Biopsy
Lymph Node Excision
Cytogenetics
Capsules
Cell Biology
Young Adult
Neoplasms
Extremities
Joints
Head
Tomography

Keywords

  • Fine needle aspiration
  • Synovial sarcoma
  • Thyroid

Cite this

Jang, Ki Seok ; Min, Kyueng Whan ; Jang, Si Hyong ; Seung, Sam Paik ; Tae, Kyung ; Se, Jin Jang ; Moon, Hyang Park. / Primary synovial sarcoma of the thyroid gland. In: Journal of Korean Medical Science. 2007 ; Vol. 22, No. SUPPL. pp. S154-S158.
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Jang, KS, Min, KW, Jang, SH, Seung, SP, Tae, K, Se, JJ & Moon, HP 2007, 'Primary synovial sarcoma of the thyroid gland', Journal of Korean Medical Science, vol. 22, no. SUPPL., pp. S154-S158.

Primary synovial sarcoma of the thyroid gland. / Jang, Ki Seok; Min, Kyueng Whan; Jang, Si Hyong; Seung, Sam Paik; Tae, Kyung; Se, Jin Jang; Moon, Hyang Park.

In: Journal of Korean Medical Science, Vol. 22, No. SUPPL., 01.09.2007, p. S154-S158.

Research output: Contribution to journalArticle

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T1 - Primary synovial sarcoma of the thyroid gland

AU - Jang, Ki Seok

AU - Min, Kyueng Whan

AU - Jang, Si Hyong

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AU - Moon, Hyang Park

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