Palladium-catalyzed cycloalkylations of 2-bromo-l,n-dienes with organoboronic acids

Chang Ho Oh, Hye Rhyan Sung, Su Jin Park, Kyo Han Ahn

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Cascade palladium-catalyzed cycloalkylations of 2-bromo-1,n-dienes were accomplished in good to excellent yields, where the alkylpalladium intermediates, formed via an intramolecular Heck reaction of 2-bromo-1,n-dienes (n = 6 or 7), were successfully cross-coupled with various organoboronic acids. The optimal yields were achieved by the use of cesium carbonate in ethanol with Pd(PPh3)4 as catalyst, with 2-bromo-1,n-dienes and organoboronic acids at concentrations of 0.2 and 0.3 M (1.5 equiv), respectively.

Original languageEnglish
Pages (from-to)7155-7157
Number of pages3
JournalJournal of Organic Chemistry
Volume67
Issue number20
DOIs
StatePublished - 2002 Oct 4

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Palladium
Acids
Ethanol
Catalysts
cesium carbonate

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Oh, Chang Ho ; Sung, Hye Rhyan ; Park, Su Jin ; Ahn, Kyo Han. / Palladium-catalyzed cycloalkylations of 2-bromo-l,n-dienes with organoboronic acids. In: Journal of Organic Chemistry. 2002 ; Vol. 67, No. 20. pp. 7155-7157.
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Palladium-catalyzed cycloalkylations of 2-bromo-l,n-dienes with organoboronic acids. / Oh, Chang Ho; Sung, Hye Rhyan; Park, Su Jin; Ahn, Kyo Han.

In: Journal of Organic Chemistry, Vol. 67, No. 20, 04.10.2002, p. 7155-7157.

Research output: Contribution to journalArticle

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