Highly sensitive detection of dipicolinic acid with a water-dispersible terbium-metal organic framework

Neha Bhardwaj, Sanjeev Bhardwaj, Jyotsana Mehta, Ki Hyun Kim, Akash Deep

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

The sensitive detection of dipicolinic acid (DPA) is strongly associated with the sensing of bacterial organisms in food and many types of environmental samples. To date, the demand for a sensitive detection method for bacterial toxicity has increased remarkably. Herein, we investigated the DPA detection potential of a water-dispersible terbium-metal organic framework (Tb-MOF) based on the fluorescence quenching mechanism. The Tb-MOF showed a highly sensitive ability to detect DPA at a limit of detection of 0.04 nM (linear range of detection: 1 nM to 5 µM) and also offered enhanced selectivity from other commonly associated organic molecules. The present study provides a basis for the application of Tb-MOF for direct, convenient, highly sensitive, and specific detection of DPA in the actual samples.

Original languageEnglish
Pages (from-to)799-804
Number of pages6
JournalBiosensors and Bioelectronics
Volume86
DOIs
StatePublished - 2016 Dec 15

Keywords

  • Dipicolinic acid
  • Fluorescence
  • Metal organic framework
  • Sensor
  • Terbium

Fingerprint Dive into the research topics of 'Highly sensitive detection of dipicolinic acid with a water-dispersible terbium-metal organic framework'. Together they form a unique fingerprint.

  • Cite this