Graphene nanoplatelet/graphitized nanodiamond-based nanocomposite for mediator-free electrochemical sensing of urea

Vanish Kumar, Inderpreet Kaur, Saloni Arora, Ravi Mehla, Kowsalya Vellingiri, Ki-Hyun Kim

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Urea is well-known to offer tremendous scope for sensing/diagnosing such as adulteration in dairy products or diseases in human body. This study was organized to describe and validate a new mediator-free, unsophisticated, and direct current voltage (IV)-based sensor for facile detection of urea using nanocomposites made of urease-immobilized graphene nanoplatelets and graphitized nanodiamonds. This nanocomposite displayed sensitive and direct signal in the form of current at 0 V without the need of any complex chemical reaction. This platform was highly sensitive (limit of detection of 5 μg/mL) far superior to the comparable systems introduced recently. The incorporation of graphitized nanodiamonds within the graphene nanoplatelets layers helped improve the sensitivity by a factor of three (up to 806.3 µA (mg mL−1)−1 cm−2) with 20 s response time. As such, the use of this nanocomposite was helpful in improving sensing performances with enhanced enzyme loading capacity.

Original languageEnglish
Article number125375
JournalFood Chemistry
Volume303
DOIs
StatePublished - 2020 Jan 15

Fingerprint

nanodiamonds
Nanodiamonds
nanocomposites
Nanocomposites
Graphite
Urea
urea
Dairy products
Dairy Products
Urease
adulterated products
urease
chemical reactions
Human Body
human diseases
dairy products
Reaction Time
Limit of Detection
Chemical reactions
detection limit

Keywords

  • Graphene nanoplatelets
  • Graphitized nanodiamonds
  • Screen-printed electrode
  • Sensing
  • Urea

Cite this

Kumar, Vanish ; Kaur, Inderpreet ; Arora, Saloni ; Mehla, Ravi ; Vellingiri, Kowsalya ; Kim, Ki-Hyun. / Graphene nanoplatelet/graphitized nanodiamond-based nanocomposite for mediator-free electrochemical sensing of urea. In: Food Chemistry. 2020 ; Vol. 303.
@article{163d79fbd36a4283acfd127d3a1c2f78,
title = "Graphene nanoplatelet/graphitized nanodiamond-based nanocomposite for mediator-free electrochemical sensing of urea",
abstract = "Urea is well-known to offer tremendous scope for sensing/diagnosing such as adulteration in dairy products or diseases in human body. This study was organized to describe and validate a new mediator-free, unsophisticated, and direct current voltage (IV)-based sensor for facile detection of urea using nanocomposites made of urease-immobilized graphene nanoplatelets and graphitized nanodiamonds. This nanocomposite displayed sensitive and direct signal in the form of current at 0 V without the need of any complex chemical reaction. This platform was highly sensitive (limit of detection of 5 μg/mL) far superior to the comparable systems introduced recently. The incorporation of graphitized nanodiamonds within the graphene nanoplatelets layers helped improve the sensitivity by a factor of three (up to 806.3 µA (mg mL−1)−1 cm−2) with 20 s response time. As such, the use of this nanocomposite was helpful in improving sensing performances with enhanced enzyme loading capacity.",
keywords = "Graphene nanoplatelets, Graphitized nanodiamonds, Screen-printed electrode, Sensing, Urea",
author = "Vanish Kumar and Inderpreet Kaur and Saloni Arora and Ravi Mehla and Kowsalya Vellingiri and Ki-Hyun Kim",
year = "2020",
month = "1",
day = "15",
doi = "10.1016/j.foodchem.2019.125375",
language = "English",
volume = "303",
journal = "Food Chemistry",
issn = "0308-8146",

}

Graphene nanoplatelet/graphitized nanodiamond-based nanocomposite for mediator-free electrochemical sensing of urea. / Kumar, Vanish; Kaur, Inderpreet; Arora, Saloni; Mehla, Ravi; Vellingiri, Kowsalya; Kim, Ki-Hyun.

In: Food Chemistry, Vol. 303, 125375, 15.01.2020.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Graphene nanoplatelet/graphitized nanodiamond-based nanocomposite for mediator-free electrochemical sensing of urea

AU - Kumar, Vanish

AU - Kaur, Inderpreet

AU - Arora, Saloni

AU - Mehla, Ravi

AU - Vellingiri, Kowsalya

AU - Kim, Ki-Hyun

PY - 2020/1/15

Y1 - 2020/1/15

N2 - Urea is well-known to offer tremendous scope for sensing/diagnosing such as adulteration in dairy products or diseases in human body. This study was organized to describe and validate a new mediator-free, unsophisticated, and direct current voltage (IV)-based sensor for facile detection of urea using nanocomposites made of urease-immobilized graphene nanoplatelets and graphitized nanodiamonds. This nanocomposite displayed sensitive and direct signal in the form of current at 0 V without the need of any complex chemical reaction. This platform was highly sensitive (limit of detection of 5 μg/mL) far superior to the comparable systems introduced recently. The incorporation of graphitized nanodiamonds within the graphene nanoplatelets layers helped improve the sensitivity by a factor of three (up to 806.3 µA (mg mL−1)−1 cm−2) with 20 s response time. As such, the use of this nanocomposite was helpful in improving sensing performances with enhanced enzyme loading capacity.

AB - Urea is well-known to offer tremendous scope for sensing/diagnosing such as adulteration in dairy products or diseases in human body. This study was organized to describe and validate a new mediator-free, unsophisticated, and direct current voltage (IV)-based sensor for facile detection of urea using nanocomposites made of urease-immobilized graphene nanoplatelets and graphitized nanodiamonds. This nanocomposite displayed sensitive and direct signal in the form of current at 0 V without the need of any complex chemical reaction. This platform was highly sensitive (limit of detection of 5 μg/mL) far superior to the comparable systems introduced recently. The incorporation of graphitized nanodiamonds within the graphene nanoplatelets layers helped improve the sensitivity by a factor of three (up to 806.3 µA (mg mL−1)−1 cm−2) with 20 s response time. As such, the use of this nanocomposite was helpful in improving sensing performances with enhanced enzyme loading capacity.

KW - Graphene nanoplatelets

KW - Graphitized nanodiamonds

KW - Screen-printed electrode

KW - Sensing

KW - Urea

UR - http://www.scopus.com/inward/record.url?scp=85071488514&partnerID=8YFLogxK

U2 - 10.1016/j.foodchem.2019.125375

DO - 10.1016/j.foodchem.2019.125375

M3 - Article

VL - 303

JO - Food Chemistry

JF - Food Chemistry

SN - 0308-8146

M1 - 125375

ER -