Functional insights of plant GSK3-like kinases: Multi-taskers in diverse cellular signal transduction pathways

Ji Hyun Youn, Tae-Wuk Kim

Research output: Contribution to journalReview article

44 Citations (Scopus)

Abstract

The physiological importance of GSK3-like kinases in plants emerged when the functional role of plant GSK3-like kinases represented by BIN2 was first elucidated in the brassinosteroid (BR)-regulated signal transduction pathway. While early studies focused more on understanding how GSK3-like kinases regulate BR signaling, recent studies have implicated many novel substrates of GSK3-like kinases that are involved in a variety of cellular processes as well as BR signaling. Plant GSK3-like kinases play diverse roles in physiological and developmental processes such as cell growth, root and stomatal cell development, flower development, xylem differentiation, light response, and stress responses. Here, we review the progress made in recent years in understanding the versatile functions of plant GSK3-like kinases. Based on the relationship between GSK3-like kinases and their newly identified substrates, we discuss the physiological and biochemical relevance of various cellular signaling mediated by GSK3-like kinases in plants.

Original languageEnglish
Pages (from-to)552-565
Number of pages14
JournalMolecular Plant
Volume8
Issue number4
DOIs
StatePublished - 2015 Apr 6

Fingerprint

signal transduction
Signal Transduction
phosphotransferases (kinases)
Phosphotransferases
Brassinosteroids
brassinosteroids
Physiological Phenomena
Xylem
cell communication
xylem
cell growth
stress response
flowering
Light
Growth
cells

Keywords

  • Arabidopsis
  • GSK3-like kinases
  • brassinosteroids
  • rice
  • signal transduction pathway

Cite this

@article{c4abe37de9f044a2af6a657e9e8b4ab6,
title = "Functional insights of plant GSK3-like kinases: Multi-taskers in diverse cellular signal transduction pathways",
abstract = "The physiological importance of GSK3-like kinases in plants emerged when the functional role of plant GSK3-like kinases represented by BIN2 was first elucidated in the brassinosteroid (BR)-regulated signal transduction pathway. While early studies focused more on understanding how GSK3-like kinases regulate BR signaling, recent studies have implicated many novel substrates of GSK3-like kinases that are involved in a variety of cellular processes as well as BR signaling. Plant GSK3-like kinases play diverse roles in physiological and developmental processes such as cell growth, root and stomatal cell development, flower development, xylem differentiation, light response, and stress responses. Here, we review the progress made in recent years in understanding the versatile functions of plant GSK3-like kinases. Based on the relationship between GSK3-like kinases and their newly identified substrates, we discuss the physiological and biochemical relevance of various cellular signaling mediated by GSK3-like kinases in plants.",
keywords = "Arabidopsis, GSK3-like kinases, brassinosteroids, rice, signal transduction pathway",
author = "Youn, {Ji Hyun} and Tae-Wuk Kim",
year = "2015",
month = "4",
day = "6",
doi = "10.1016/j.molp.2014.12.006",
language = "English",
volume = "8",
pages = "552--565",
journal = "Molecular Plant",
issn = "1674-2052",
number = "4",

}

Functional insights of plant GSK3-like kinases : Multi-taskers in diverse cellular signal transduction pathways. / Youn, Ji Hyun; Kim, Tae-Wuk.

In: Molecular Plant, Vol. 8, No. 4, 06.04.2015, p. 552-565.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Functional insights of plant GSK3-like kinases

T2 - Multi-taskers in diverse cellular signal transduction pathways

AU - Youn, Ji Hyun

AU - Kim, Tae-Wuk

PY - 2015/4/6

Y1 - 2015/4/6

N2 - The physiological importance of GSK3-like kinases in plants emerged when the functional role of plant GSK3-like kinases represented by BIN2 was first elucidated in the brassinosteroid (BR)-regulated signal transduction pathway. While early studies focused more on understanding how GSK3-like kinases regulate BR signaling, recent studies have implicated many novel substrates of GSK3-like kinases that are involved in a variety of cellular processes as well as BR signaling. Plant GSK3-like kinases play diverse roles in physiological and developmental processes such as cell growth, root and stomatal cell development, flower development, xylem differentiation, light response, and stress responses. Here, we review the progress made in recent years in understanding the versatile functions of plant GSK3-like kinases. Based on the relationship between GSK3-like kinases and their newly identified substrates, we discuss the physiological and biochemical relevance of various cellular signaling mediated by GSK3-like kinases in plants.

AB - The physiological importance of GSK3-like kinases in plants emerged when the functional role of plant GSK3-like kinases represented by BIN2 was first elucidated in the brassinosteroid (BR)-regulated signal transduction pathway. While early studies focused more on understanding how GSK3-like kinases regulate BR signaling, recent studies have implicated many novel substrates of GSK3-like kinases that are involved in a variety of cellular processes as well as BR signaling. Plant GSK3-like kinases play diverse roles in physiological and developmental processes such as cell growth, root and stomatal cell development, flower development, xylem differentiation, light response, and stress responses. Here, we review the progress made in recent years in understanding the versatile functions of plant GSK3-like kinases. Based on the relationship between GSK3-like kinases and their newly identified substrates, we discuss the physiological and biochemical relevance of various cellular signaling mediated by GSK3-like kinases in plants.

KW - Arabidopsis

KW - GSK3-like kinases

KW - brassinosteroids

KW - rice

KW - signal transduction pathway

UR - http://www.scopus.com/inward/record.url?scp=84926304360&partnerID=8YFLogxK

U2 - 10.1016/j.molp.2014.12.006

DO - 10.1016/j.molp.2014.12.006

M3 - Review article

C2 - 25655825

AN - SCOPUS:84926304360

VL - 8

SP - 552

EP - 565

JO - Molecular Plant

JF - Molecular Plant

SN - 1674-2052

IS - 4

ER -