Effect of surface structure on biomechanical properties and osseointegration

Baek Hee Lee, Changyang Lee, Dae Gun Kim, Kuiwon Choi, Kyu Hwan Lee, Young Do Kim

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The purpose of this study is to improve the bone-bonding ability between titanium implants and living bone through the control of geometric design and chemical compositions of an implant surface. We compared the tissue healing response and resulting implant stability for three surface designs by characterizing the histological and mechanical properties of the healing tissue around smooth-surfaced Ti-6Al-4V (SS), CP-Ti plasma-spray-coated (PSC), alkali- and heat-treated (AHT) implants. The implants were transversely inserted into a dog thighbone and evaluated at 4, 8, and 12 weeks. Histological examination indicated that initial matrix mineralization leading to osseointegration occurred more rapidly with the AHT implant. During the 4, 8, and 12 week healing periods, new bone on the surface of AHT implant showed denser growth than that on the SS and PSC implants. The more extensive tissue integration and more rapid matrix mineralization with the AHT implant were reflected in the mechanical test data, which demonstrated superior attachment strength and interfacial stiffness for the AHT implant after healing for 4, 8 and 12 weeks of healing because of the mechanical interlocking in the micrometer sized rough surface and the large bonding area between bone and implant caused by the nanosized porous surface structure. Histological and mechanical data demonstrate that with the appropriate surface design selection, bone bone-bonding ability can be improved and can induce acceleration of the healing response, thereby improving the potential for implant osseointegration.

Original languageEnglish
Pages (from-to)1448-1461
Number of pages14
JournalMaterials Science and Engineering C
Volume28
Issue number8
DOIs
StatePublished - 2008 Dec 1

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healing
Surface structure
bones
Alkalies
Bone
alkalies
heat
Tissue
sprayers
Plasmas
dogs
matrices
Titanium
locking
attachment
micrometers
stiffness
chemical composition
titanium
examination

Keywords

  • Chemical treatment
  • In vivo
  • Osseointegration
  • Surface modification
  • Titanium implant

Cite this

Lee, Baek Hee ; Lee, Changyang ; Kim, Dae Gun ; Choi, Kuiwon ; Lee, Kyu Hwan ; Kim, Young Do. / Effect of surface structure on biomechanical properties and osseointegration. In: Materials Science and Engineering C. 2008 ; Vol. 28, No. 8. pp. 1448-1461.
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Effect of surface structure on biomechanical properties and osseointegration. / Lee, Baek Hee; Lee, Changyang; Kim, Dae Gun; Choi, Kuiwon; Lee, Kyu Hwan; Kim, Young Do.

In: Materials Science and Engineering C, Vol. 28, No. 8, 01.12.2008, p. 1448-1461.

Research output: Contribution to journalArticle

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