Abstract
The authors assessed the influence of cholecystokinin (CCK), administered before cholescintigraphy, on the biliary-to-bowel transit time (BBTT) of technetium-99m disofenin. Fourteen healthy volunteers underwent two separate cholescintigraphic studies with and without CCK treatment. BBTT was less then 1 hour in all 14 studies of subjects not treated with CCK. In 14 subjects treated with CCK, there was no tracer activity in the bowel up to 2 hours in seven (50%) (P = .006). Eighty-three cholescintigrams obtained in patients with suspected acute cholecystitis were also retrospectively analyzed. In 53 of 83 patients in whom the gallbladder was visualized within 1 hour, significantly delayed BBTT was found in 14 of 29 (48%) who received CCK, compared with the BBTT in one of 24 patients (4%) who did not receive CCK (P < .001). In the 30 patients in whom the gallbladder was never visualized (n = 28) or was visualized after 1 hour (n = 2), BBTT was less than 30 minutes, regardless of whether patients were treated with CCK. Results show that CCK treatment causes significantly delayed BBTT in many cases, and this finding should not be interpreted as abnormal.
| Original language | English |
|---|---|
| Pages (from-to) | 553-556 |
| Number of pages | 4 |
| Journal | Radiology |
| Volume | 176 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1990 Jan 1 |
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Delayed biliary-to-bowel transit in cholescintigraphy after cholecystokinin treatment. / Kim, Chun Ki; Palestro, C. J.; Solomon, R. W.; Molinari, D. S.; Lee, S. O.; Goldsmith, S. J.
In: Radiology, Vol. 176, No. 2, 01.01.1990, p. 553-556.Research output: Contribution to journal › Article
TY - JOUR
T1 - Delayed biliary-to-bowel transit in cholescintigraphy after cholecystokinin treatment
AU - Kim, Chun Ki
AU - Palestro, C. J.
AU - Solomon, R. W.
AU - Molinari, D. S.
AU - Lee, S. O.
AU - Goldsmith, S. J.
PY - 1990/1/1
Y1 - 1990/1/1
N2 - The authors assessed the influence of cholecystokinin (CCK), administered before cholescintigraphy, on the biliary-to-bowel transit time (BBTT) of technetium-99m disofenin. Fourteen healthy volunteers underwent two separate cholescintigraphic studies with and without CCK treatment. BBTT was less then 1 hour in all 14 studies of subjects not treated with CCK. In 14 subjects treated with CCK, there was no tracer activity in the bowel up to 2 hours in seven (50%) (P = .006). Eighty-three cholescintigrams obtained in patients with suspected acute cholecystitis were also retrospectively analyzed. In 53 of 83 patients in whom the gallbladder was visualized within 1 hour, significantly delayed BBTT was found in 14 of 29 (48%) who received CCK, compared with the BBTT in one of 24 patients (4%) who did not receive CCK (P < .001). In the 30 patients in whom the gallbladder was never visualized (n = 28) or was visualized after 1 hour (n = 2), BBTT was less than 30 minutes, regardless of whether patients were treated with CCK. Results show that CCK treatment causes significantly delayed BBTT in many cases, and this finding should not be interpreted as abnormal.
AB - The authors assessed the influence of cholecystokinin (CCK), administered before cholescintigraphy, on the biliary-to-bowel transit time (BBTT) of technetium-99m disofenin. Fourteen healthy volunteers underwent two separate cholescintigraphic studies with and without CCK treatment. BBTT was less then 1 hour in all 14 studies of subjects not treated with CCK. In 14 subjects treated with CCK, there was no tracer activity in the bowel up to 2 hours in seven (50%) (P = .006). Eighty-three cholescintigrams obtained in patients with suspected acute cholecystitis were also retrospectively analyzed. In 53 of 83 patients in whom the gallbladder was visualized within 1 hour, significantly delayed BBTT was found in 14 of 29 (48%) who received CCK, compared with the BBTT in one of 24 patients (4%) who did not receive CCK (P < .001). In the 30 patients in whom the gallbladder was never visualized (n = 28) or was visualized after 1 hour (n = 2), BBTT was less than 30 minutes, regardless of whether patients were treated with CCK. Results show that CCK treatment causes significantly delayed BBTT in many cases, and this finding should not be interpreted as abnormal.
UR - http://www.scopus.com/inward/record.url?scp=0025356684&partnerID=8YFLogxK
U2 - 10.1148/radiology.176.2.2367674
DO - 10.1148/radiology.176.2.2367674
M3 - Article
C2 - 2367674
AN - SCOPUS:0025356684
VL - 176
SP - 553
EP - 556
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 2
ER -