Chiral Resolution of Racemic 2-Pyrone Diels-Alder Cycloadduct by Diastereomeric Salt Formation

Tae Hong Jeon, Hyung Joon Kang, Anastasia Svirid, Alexander Lyakhov, Vitaly Kovalenko, Cheon-Gyu Cho

Research output: Contribution to journalArticle

Abstract

An efficient protocol was developed that allows resolution of racemic bicyclolactone carboxylic acid obtained from the Diels-Alder cycloaddition of 3,5-dibromo-2-pyrone by formation of diastereomeric salts with quinidine and cinchonidine.

Original languageEnglish
JournalBulletin of the Korean Chemical Society
DOIs
Publication statusAccepted/In press - 2019 Jan 1

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Keywords

  • 3,5-dibromo-2-pyrone
  • Chiral resolution
  • Diastereomeric salt
  • Diels–Alder reaction

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