A review of the applications of Schiff bases as optical chemical sensors

Asnake Lealem Berhanu, Gaurav, Irshad Mohiuddin, Ashok Kumar Malik, Jatinder Singh Aulakh, Vanish Kumar, Ki Hyun Kim

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations


Schiff bases and their metal complexes have become well-known for catalytic (e.g., in various synthetic processes) and biological properties (e.g., antifungal, antibacterial, anti-malarial, and antiviral characteristics) since their discovery by Hugo Schiff in 1864. As synthetic compounds, they are employed as versatile tools in numerous applications such as fluorescent turn-on/turn-off sensors for the determination of diverse analytes (e.g., metallic components). As such, they can offer a way to identify toxic ions and/or to provide their speciation in environmental media. This review covers a broad range of Schiff bases that are used in sensing applications for metallic cations and anions in various kinds of environmental and biological media.

Original languageEnglish
Pages (from-to)74-91
Number of pages18
JournalTrAC - Trends in Analytical Chemistry
StatePublished - 2019 Jul
Externally publishedYes


  • Azomethine
  • Chemosensors
  • Fluorescent probe
  • Ligand
  • Schiff base


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