• 4320 Citations
  • 35 h-Index
1992 …2020

Research output per year

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Research Output

2020

CD64-targeted HO-1 RNA interference enhances chemosensitivity in orthotopic model of acute myeloid leukemia and patient-derived bone marrow cells

Yong, S. B., Chung, J. Y., Kim, S. S., Choi, H. S. & Kim, Y. H., 2020 Feb, In : Biomaterials. 230, 119651.

Research output: Contribution to journalArticle

2 Scopus citations

Heme Oxygenase 1-Targeted Hybrid Nanoparticle for Chemo- and Immuno-Combination Therapy in Acute Myelogenous Leukemia

Yong, S. B., Kim, J., Chung, J. Y., Ra, S., kim, S. S. & Kim, Y. H., 2020 Jul 1, In : Advanced Science. 7, 13, 2000487.

Research output: Contribution to journalArticle

Open Access

Synthesis and cellular affinity of a water-soluble sulfated diselenide compound as a H2O2-responsive ionic cross-linker

Lee, E., Park, H. C., Lee, D., Park, S. J., Kim, Y. H. & Kim, C. H., 2020 Mar 25, In : Journal of Industrial and Engineering Chemistry. 83, p. 181-188 8 p.

Research output: Contribution to journalArticle

2019

Non-viral nano-immunotherapeutics targeting tumor microenvironmental immune cells

Yong, S. B., Chung, J. Y., Song, Y., Kim, J., Ra, S. & Kim, Y. H., 2019 Oct, In : Biomaterials. 219, 119401.

Research output: Contribution to journalReview article

6 Scopus citations

Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance

Chung, J. Y., Ul Ain, Q., Song, Y., Yong, S. B. & Kim, Y. H., 2019 Jan 1, In : Genome Research. 29, 9, p. 1442-1452 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson’s disease models

Kang, Y. C., Son, M., Kang, S., Im, S., Piao, Y., Lim, K. S., Song, M. Y., Park, K. S., Kim, Y. H. & Pak, Y. K., 2018 Aug 1, In : Experimental and Molecular Medicine. 50, 8, 105.

Research output: Contribution to journalArticle

6 Scopus citations

Recent challenges and advances in genetically-engineered cell therapy

Yong, S. B., Chung, J. Y., Song, Y. & Kim, Y. H., 2018 Mar 1, In : Journal of Pharmaceutical Investigation. 48, 2, p. 199-208 10 p.

Research output: Contribution to journalReview article

7 Scopus citations

Regeneration of Anti-Hypoxic Myocardial Cells by Transduction of Mesenchymal Stem Cell-Derived Exosomes Containing Tat-Metallothionein Fusion Proteins

Ain, Q. U., Woo, Y. S., Chung, J. Y. & Kim, Y. H., 2018 Aug 1, In : Macromolecular Research. 26, 8, p. 709-716 8 p.

Research output: Contribution to journalArticle

Surfactant-free solubilization and systemic delivery of anti-cancer drug using low molecular weight methylcellulose

Chung, J. Y., Ko, J. H., Lee, Y. J., Choi, H. S. & Kim, Y. H., 2018 Apr 28, In : Journal of Controlled Release. 276, p. 42-49 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017
4 Scopus citations

Enhanced Systemic Anti-Angiogenic siVEGF Delivery Using PEGylated Oligo- d -arginine

Chung, J. Y., Ul Ain, Q., Lee, H. L., Kim, S. M. & Kim, Y. H., 2017 Sep 5, In : Molecular Pharmaceutics. 14, 9, p. 3059-3068 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Human CD64-targeted non-viral siRNA delivery system for blood monocyte gene modulation

Yong, S. B., Kim, H. J., Kim, J. K., Chung, J. Y. & Kim, Y. H., 2017 Feb 7, In : Scientific reports. 7, 42171.

Research output: Contribution to journalArticle

3 Scopus citations

Immunomodulation of cell-penetrating tat-metallothionein for successful outcome of xenotransplanted pancreatic islet

Kim, M. J., Hwang, Y. H., Kim, Y. H. & Lee, D. Y., 2017 Apr 21, In : Journal of Drug Targeting. 25, 4, p. 350-359 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mononuclear phagocytes as a target, not a barrier, for drug delivery

Yong, S. B., Song, Y., Kim, H. J., Ain, Q. U. & Kim, Y. H., 2017 Aug 10, In : Journal of Controlled Release. 259, p. 53-61 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Visceral adipose tissue macrophage-targeted TACE silencing to treat obesity-induced type 2 diabetes

Yong, S. B., Song, Y. & Kim, Y-H., 2017 Dec 1, In : Biomaterials. 148, p. 81-89 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Effects of protein transduction domain (PTD) selection and position for improved intracellular delivery of PTD-Hsp27 fusion protein formulations

Ul Ain, Q., Lee, J. H., Woo, Y. S. & Kim, Y. H., 2016 Sep 1, In : Archives of Pharmacal Research. 39, 9, p. 1266-1274 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

RNAi-mediated silencing of TNF-α converting enzyme to down-regulate soluble TNF-α production for treatment of acute and chronic colitis

Song, Y., Kim, Y. R., Kim, S. M., Ul Ain, Q., Jang, K., Yang, C. S. & Kim, Y. H., 2016 Oct 10, In : Journal of Controlled Release. 239, p. 231-241 11 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Cardiac usage of reducible poly(oligo-D-arginine) as a gene carrier for vascular endothelial growth factor expression

Woo, J., Bae, S. H., Kim, B., Park, J. S., Jung, S., Lee, M., Kim, Y. H. & Choi, D., 2015 Dec 1, In : PLoS ONE. 10, 12, e0144491.

Research output: Contribution to journalArticle

2 Scopus citations

Current and future delivery systems for engineered nucleases: ZFN, TALEN and RGEN

Ain, Q. U., Chung, J. Y. & Kim, Y. H., 2015 Jan 6, In : Journal of Controlled Release. 205, p. 120-127 8 p.

Research output: Contribution to journalReview article

60 Scopus citations

Inhibition of cisplatin-resistance by RNA interference targeting metallothionein using reducible oligo-peptoplex

Lee, J. H., Chae, J. W., Kim, J. K., Kim, H. J., Chung, J. Y. & Kim, Y. H., 2015 Aug 4, In : Journal of Controlled Release. 215, p. 82-90 9 p., 7762.

Research output: Contribution to journalArticle

12 Scopus citations

Intracellular transduction of TAT-Hsp27 fusion protein enhancing cell survival and regeneration capacity of cardiac stem cells in acute myocardial infarction

Kim, H. J., Kim, M. H., Kim, J. T., Lee, W. J., Kim, E., Lim, K. S., Kim, J. K., Yang, Y. I., Park, K. D. & Kim, Y. H., 2015 Aug 11, In : Journal of Controlled Release. 215, p. 55-72 18 p., 7773.

Research output: Contribution to journalArticle

7 Scopus citations

Reducible Poly(Oligo- d -Arginine) as an Efficient Carrier of the Thymidine Kinase Gene in the Intracranial Glioblastoma Animal Model

Kim, H. A., Lee, H. L., Choi, E., Kim, Y. H. & Lee, M., 2015 Nov 1, In : Journal of Pharmaceutical Sciences. 104, 11, p. 3743-3751 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Nanobiomaterials for pharmaceutical and medical applications

Lee, H. & Kim, Y. H., 2014 Jan 1, In : Archives of Pharmacal Research. 37, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorial

6 Scopus citations

Natural and synthetic biomaterials for controlled drug delivery

Kim, J. K., Kim, H. J., Chung, J. Y., Lee, J. H., Young, S. B. & Kim, Y. H., 2014 Jan 1, In : Archives of Pharmacal Research. 37, 1, p. 60-68 9 p.

Research output: Contribution to journalReview article

66 Scopus citations

Oligopeptide complex for targeted non-viral gene delivery to adipocytes

Won, Y. W., Adhikary, P. P., Lim, K. S., Kim, H. J., Kim, J. K. & Kim, Y. H., 2014 Dec 1, In : Nature Materials. 13, 12, p. 1157-1164 8 p.

Research output: Contribution to journalArticle

61 Scopus citations
19 Scopus citations
2013

Dual-mode enhancement of metallothionein protein with cell transduction and retention peptide fusion

Lim, K. S., Lim, M. H., Won, Y. W., Kim, J. K., Kang, Y. C., Park, E. J., Chae, J. W., Kim, S. M., Ryu, S. E., Pak, Y. K. & Kim, Y. H., 2013 Jan 1, In : Journal of Controlled Release. 171, 2, p. 193-200 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hypoxic resistance of hypodermically transplanted pancreatic islets by using cell-absorbable antioxidant Tat-metallothionein

Jung, H. S., Lim, K. S., Kim, M. J., Hwang, Y. H., Yoo, C., Lee, Y. K., Kim, Y. H. & Lee, D. Y., 2013 Nov 14, In : Journal of Controlled Release. 172, 3, p. 1092-1101 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Injectable microsphere/hydrogel hybrid system containing heat shock protein as therapy in a murine myocardial infarction model

Lee, J., Cha, M. J., Lim, K. S., Kim, J. K., Lee, S. K., Kim, Y. H., Hwang, K. C. & Lee, K. Y., 2013 Nov 1, In : Journal of Drug Targeting. 21, 9, p. 822-829 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Protective effects of protein transduction domain-metallothionein fusion proteins against hypoxia- and oxidative stress-induced apoptosis in an ischemia/reperfusion rat model

Lim, K. S., Cha, M. J., Kim, J. K., Park, E. J., Chae, J. W., Rhim, T., Hwang, K. C. & Kim, Y. H., 2013 Jan 1, In : Journal of Controlled Release. 169, 3, p. 306-312 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Sequential delivery of TAT-HSP27 and VEGF using microsphere/hydrogel hybrid systems for therapeutic angiogenesis

Shin, S. H., Lee, J., Lim, K. S., Rhim, T., Lee, S. K., Kim, Y. H. & Lee, K. Y., 2013 Feb 28, In : Journal of Controlled Release. 166, 1, p. 38-45 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2012

A convenient method for producing the bleomycin-induced mouse model of scleroderma by weekly injections using a methylcellulose gel

Jun, J. B., Kim, J. K., Na, Y. I., Jang, S. M., Paik, S. S. & Kim, Y. H., 2012 May 1, In : Rheumatology International. 32, 5, p. 1443-1447 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Low-molecular-weight methylcellulose-based thermo-reversible gel/pluronic micelle combination system for local and sustained docetaxel delivery

Kim, J. K., Won, Y. W., Lim, K. S. & Kim, Y-H., 2012 Feb 1, In : Pharmaceutical Research. 29, 2, p. 525-534 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Self-assembled nanoparticles with dual effects of passive tumor targeting and cancer-selective anticancer effects

Won, Y. W., Yoon, S. M., Lim, K. S. & Kim, Y. H., 2012 Mar 21, In : Advanced Functional Materials. 22, 6, p. 1199-1208 10 p.

Research output: Contribution to journalArticle

30 Scopus citations
2011

Anti-cancer effects of docetaxel loaded thermo-reversible hydrogels in a tumor xenograft mice model.

Kim, J. K., Won, Y. W., Lim, K. S., Park, E. J. & Kim, Y. H., 2011 Nov 30, In : Journal of controlled release : official journal of the Controlled Release Society. 152 Suppl 1, p. e44-45

Research output: Contribution to journalArticle

Intracellular organelle-targeted non-viral gene delivery systems

Won, Y. W., Lim, K. S. & Kim, Y. H., 2011 May 30, In : Journal of Controlled Release. 152, 1, p. 99-109 11 p.

Research output: Contribution to journalReview article

64 Scopus citations

Nano self-assembly of recombinant human gelatin conjugated with α-tocopheryl succinate for Hsp90 inhibitor, 17-AAG, delivery

Won, Y. W., Yoon, S. M., Sonn, C. H., Lee, K. M. & Kim, Y-H., 2011 May 24, In : ACS Nano. 5, 5, p. 3839-3848 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

Poly(oligo-D-arginine) with internal disulfide linkages as a cytoplasm-sensitive carrier for siRNA delivery

Won, Y. W., Yoon, S. M., Lee, K. M. & Kim, Y. H., 2011 Feb, In : Molecular Therapy. 19, 2, p. 372-380 9 p.

Research output: Contribution to journalArticle

71 Scopus citations

Preparation and characterization of alpha-tricalcium phosphate cements incorporated with polyamino acids

Lee, H. S., Kwon, S. Y., Seo, E. M., Kim, Y-H. & Kim, S. S., 2011 Jan 1, In : Macromolecular Research. 19, 1, p. 90-96 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Suicidal gene therapy against tumor using reducible poly (oligo-D-arginine).

Kim, K. M., Won, Y. W., Adhikary, P. P., Hwang, Y. M. & Kim, Y-H., 2011 Jan 1, In : Journal of controlled release : official journal of the Controlled Release Society. 152 Suppl 1

Research output: Contribution to journalArticle

1 Scopus citations

Suicide gene therapy using reducible poly (oligo-d-arginine) for the treatment of spinal cord tumors

Won, Y. W., Kim, K. M., An, S. S., Lee, M., Ha, Y. & Kim, Y-H., 2011 Dec 1, In : Biomaterials. 32, 36, p. 9766-9775 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Tat-enhanced delivery of metallothionein can partially prevent the development of diabetes

Park, L., Min, D., Kim, H., Chung, H. Y., Lee, C. H., Park, I. S., Kim, Y. & Park, Y., 2011 Nov 1, In : Free Radical Biology and Medicine. 51, 9, p. 1666-1674 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2010

Preparation and functional analysis of recombinant protein transduction domain-metallothionein fusion proteins

Lim, K. S., Won, Y. W., Park, Y. S. & Kim, Y. H., 2010 Aug 1, In : Biochimie. 92, 8, p. 964-970 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Prolongation and enhancement of the anti-apoptotic effects of PTD-Hsp27 fusion proteins using an injectable thermo-reversible gel in a rat myocardial infarction model

Won, Y. W., Kim, J. K., Cha, M. J., Hwang, K. C., Choi, D. & Kim, Y. H., 2010 Jun 1, In : Journal of Controlled Release. 144, 2, p. 181-189 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Reducible poly(oligo-d-arginine) for enhanced gene expression in mouse lung by intratracheal injection

Won, Y. W., Kim, H. A., Lee, M. & Kim, Y. H., 2010 Apr 1, In : Molecular Therapy. 18, 4, p. 734-742 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Therapeutic effects of a reducible poly (oligo-d-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury

Hyun, H., Won, Y. W., Kim, K. M., Lee, J., Lee, M. & Kim, Y-H., 2010 Dec 1, In : Biomaterials. 31, 34, p. 9128-9134 7 p.

Research output: Contribution to journalArticle

42 Scopus citations
2009
63 Scopus citations

Ischemic heart diseases: Current treatments and future

Choi, D., Hwang, K. C., Lee, K. Y. & Kim, Y. H., 2009 Dec 16, In : Journal of Controlled Release. 140, 3, p. 194-202 9 p.

Research output: Contribution to journalReview article

46 Scopus citations