• 5998 Citations
  • 40 h-Index
19972020

Research output per year

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Research Output

2020

A RAGE-antagonist peptide potentiates polymeric micelle-mediated intracellular delivery of plasmid DNA for acute lung injury gene therapy

Piao, C., Zhuang, C., Choi, M., Ha, J. & Lee, M., 2020 Jul 2, In : Nanoscale. 12, 25, p. 13606-13617 12 p.

Research output: Contribution to journalArticle

Systemic delivery of microRNA-21 antisense oligonucleotides to the brain using T7-peptide decorated exosomes

Kim, G., Kim, M., Lee, Y., Byun, J. W., Hwang, D. W. & Lee, M., 2020 Jan 10, In : Journal of Controlled Release. 317, p. 273-281 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Targeted delivery of Chil3/Chil4 siRNA to alveolar macrophages using ternary complexes composed of HMG and oligoarginine micelles

Choi, M., Jeong, H., Kim, S., Kim, M., Lee, M. & Rhim, T., 2020 Jan 14, In : Nanoscale. 12, 2, p. 933-943 11 p.

Research output: Contribution to journalArticle

2019

A self-assembled DNA-nanoparticle with a targeting peptide for hypoxia-inducible gene therapy of ischemic stroke

Oh, J., Lee, J., Piao, C., Jeong, J. H. & Lee, M., 2019 May 1, In : Biomaterials Science. 7, 5, p. 2174-2190 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Basic amino acids modified poly(Amidoamine) generation 2 for delivery of plasmid dna

Lee, Y. K., Thuy, L. T., Choi, J. S. & Lee, M., 2019 Jan 1, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Combined delivery of curcumin and the heme oxygenase-1 gene using cholesterol-conjugated polyamidoamine for anti-inflammatory therapy in acute lung injury

Kim, G., Piao, C., Oh, J. & Lee, M., 2019 Mar 15, In : Phytomedicine. 56, p. 165-174 10 p.

Research output: Contribution to journalArticle

2 Scopus citations
1 Scopus citations

Enrichment of vascular endothelial growth factor secreting mesenchymal stromal cells enhances therapeutic angiogenesis in a mouse model of hind limb ischemia

PARK, JIN. SIL., BAE, SEONG. E. O. N. G. H. O., JUNG, SUBIN., Lee, M. & CHOI, DONGHOON., 2019 Apr 1, In : Cytotherapy. 21, 4, p. 433-443 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Inhalable Gene Delivery System Using a Cationic RAGE-Antagonist Peptide for Gene Delivery to Inflammatory Lung Cells

Piao, C., Kim, G., Ha, J. & Lee, M., 2019 May 13, In : ACS Biomaterials Science and Engineering. 5, 5, p. 2247-2257 11 p.

Research output: Contribution to journalArticle

In vivo neuronal gene editing via CRISPR–Cas9 amphiphilic nanocomplexes alleviates deficits in mouse models of Alzheimer’s disease

Park, H., Oh, J., Shim, G., Cho, B., Chang, Y., Kim, S., Baek, S., Kim, H., Shin, J., Choi, H., Yoo, J., Kim, J., Jun, W., Lee, M., Lengner, C. J., Oh, Y. K. & Kim, J., 2019 Apr 1, In : Nature Neuroscience. 22, 4, p. 524-528 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Rage targeting therapeutic exosome for drug delivery

Kim, G. & Lee, M., 2019 Jan 1, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2018

A curcumin-loaded polymeric micelle as a carrier of a microRNA-21 antisense-oligonucleotide for enhanced anti-tumor effects in a glioblastoma animal model

Tan, X., Kim, G., Lee, D., Oh, J., Kim, M., Piao, C., Lee, J., Lee, M. S., Jeong, J. H. & Lee, M., 2018 Feb 1, In : Biomaterials Science. 6, 2, p. 407-417 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

A ternary-complex of a suicide gene, a RAGE-binding peptide, and polyethylenimine as a gene delivery system with anti-tumor and anti-angiogenic dual effects in glioblastoma

Choi, E., Oh, J., Lee, D., Lee, J., Tan, X., Kim, M., Kim, G., Piao, C. & Lee, M., 2018 Jun 10, In : Journal of Controlled Release. 279, p. 40-52 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Characterization of neural stem cells modified with hypoxia/neuron-specific VEGF expression system for spinal cord injury

Yun, Y., Oh, J., Kim, Y., Kim, G., Lee, M. & Ha, Y., 2018 Jan 1, In : Gene Therapy. 25, 1, p. 27-38 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Intranasal delivery of a Fas-blocking peptide attenuates Fas-mediated apoptosis in brain ischemia

Ullah, I., Chung, K., Oh, J., Beloor, J., Bae, S., Lee, S. C., Lee, M., Kumar, P. & Lee, S. K., 2018 Dec 1, In : Scientific reports. 8, 1, 15041.

Research output: Contribution to journalArticle

2 Scopus citations

Production and application of HMGB1 derived recombinant RAGE-antagonist peptide for anti-inflammatory therapy in acute lung injury

Lee, S., Piao, C., Kim, G., Kim, J. Y., Choi, E. & Lee, M., 2018 Mar 1, In : European Journal of Pharmaceutical Sciences. 114, p. 275-284 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

RAGE-binding peptide-conjugated polyethylenimine as a dual-functional carrier: A RAGE-mediated gene carrier and an anti-angiogenic reagent

Lee, D., Choi, E., Lee, J., Oh, J., Lee, S. & Lee, M., 2018 Nov 25, In : Journal of Industrial and Engineering Chemistry. 67, p. 284-292 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Self-assembled polymeric micelles for combined delivery of anti-inflammatory gene and drug to the lungs by inhalation

Kim, G., Piao, C., Oh, J. & Lee, M., 2018 May 14, In : Nanoscale. 10, 18, p. 8503-8514 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Therapeutic effects of a mesenchymal stem cell-based insulin-like growth factor-1/enhanced green fluorescent protein dual gene sorting system in a myocardial infarction rat model

Jung, S., Kim, J. H., Yim, C., Lee, M., Kang, H. J. & Choi, D., 2018 Dec, In : Molecular Medicine Reports. 18, 6, p. 5563-5571 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

A new combination therapy for asthma using dual-function dexamethasone-conjugated polyethylenimine and Vitamin D binding protein siRNA

Choi, M., Gu, J., Lee, M. & Rhim, T., 2017 Nov 1, In : Gene Therapy. 24, 11, p. 727-734 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Anti-cancer effect of R3V6 peptide-mediated delivery of an anti-microRNA-21 antisense-oligodeoxynucleotide in a glioblastoma animal model

Oh, B., Song, H., Lee, D., Oh, J., Kim, G., Ihm, S. H. & Lee, M., 2017 Feb 7, In : Journal of Drug Targeting. 25, 2, p. 132-139 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Anti-Inflammatory Therapeutic Effect of Adiponectin Gene Delivery Using a Polymeric Carrier in an Acute Lung Injury Model

Piao, C., Park, J. H. & Lee, M., 2017 Jul 1, In : Pharmaceutical research. 34, 7, p. 1517-1526 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Combined Delivery of a Lipopolysaccharide-Binding Peptide and the Heme Oxygenase-1 Gene Using Deoxycholic Acid-Conjugated Polyethylenimine for the Treatment of Acute Lung Injury

Kim, J. Y., Piao, C., Kim, G., Lee, S., Lee, M. S., Jeong, J. H. & Lee, M., 2017 Aug, In : Macromolecular Bioscience. 17, 8, 1600490.

Research output: Contribution to journalArticle

7 Scopus citations

Combined delivery of temozolomide and the thymidine kinase gene for treatment of glioblastoma

Choi, E., Han, J., Tan, X., Oh, J., Lee, D., Rhim, T. & Lee, M., 2017 Feb 7, In : Journal of Drug Targeting. 25, 2, p. 156-162 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Deoxycholic Acid–Conjugated Polyethylenimine for Delivery of Heme Oxygenase-1 Gene in Rat Ischemic Stroke Model

Oh, J., Lee, M. S., Jeong, J. H. & Lee, M., 2017 Dec 1, In : Journal of Pharmaceutical Sciences. 106, 12, p. 3524-3532 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gene delivery to pancreatic islets for effective transplantation in diabetic animal

Lee, M., Kim, M. J., Oh, J., Piao, C., Park, Y. W. & Lee, D. Y., 2017 Dec 25, In : Journal of Industrial and Engineering Chemistry. 56, p. 45-54 10 p.

Research output: Contribution to journalReview article

HMGB1 modulation in pancreatic islets using a cell-permeable A-box fragment

Hwang, Y. H., Kim, M. J., Lee, Y. K., Lee, M. & Lee, D. Y., 2017 Jan 28, In : Journal of Controlled Release. 246, p. 155-163 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Oral delivery of a therapeutic gene encoding glucagon-like peptide 1 to treat high fat diet-induced diabetes

Nurunnabi, M., Lee, S. A., Revuri, V., Hwang, Y. H., Kang, S. H., Lee, M., Cho, S., Cho, K. J., Byun, Y., Bae, Y. H., Lee, D. Y. & Lee, Y. K., 2017 Dec 28, In : Journal of Controlled Release. 268, p. 305-313 9 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Delivery of Hypoxia-Inducible Heme Oxygenase-1 Gene for Site-Specific Gene Therapy in the Ischemic Stroke Animal Model

Choi, M., Oh, J., Rhim, T. & Lee, M., 2016 Sep 1, In : Pharmaceutical Research. 33, 9, p. 2250-2258 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Delivery of the high-mobility group box 1 box A peptide using heparin in the acute lung injury animal models

Song, J. H., Kim, J. Y., Piao, C., Lee, S., Kim, B., Song, S. J., Choi, J. S. & Lee, M., 2016 Jul 28, In : Journal of Controlled Release. 234, p. 33-40 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Hypoxia-specific, VEGF-expressing neural stem cell therapy for safe and effective treatment of neuropathic pain

Lee, H. L., Lee, H. Y., Yun, Y., Oh, J., Che, L., Lee, M. & Ha, Y., 2016 Mar 28, In : Journal of Controlled Release. 226, p. 21-34 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Peptide micelle-mediated curcumin delivery for protection of islet β-cells under hypoxia

Han, J., Oh, J., Ihm, S. H. & Lee, M., 2016 Aug 8, In : Journal of Drug Targeting. 24, 7, p. 618-623 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Simultaneous regulation of apoptotic gene silencing and angiogenic gene expression for myocardial infarction therapy: Single-carrier delivery of SHP-1 siRNA and VEGF-expressing pDNA

Kim, D., Ku, S. H., Kim, H., Jeong, J. H., Lee, M., Kwon, I. C., Choi, D. & Kim, S. H., 2016 Dec 10, In : Journal of Controlled Release. 243, p. 182-194 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Targeted delivery of growth factors in ischemic stroke animal models

Rhim, T. & Lee, M., 2016 May 3, In : Expert Opinion on Drug Delivery. 13, 5, p. 709-723 15 p.

Research output: Contribution to journalReview article

6 Scopus citations
2015

A gene and neural stem cell therapy platform based on neuronal cell type–inducible gene overexpression

Oh, J., You, Y., Yun, Y., Lee, H. L., Yoon, D. H., Lee, M. & Ha, Y., 2015 Jul 1, In : Yonsei Medical Journal. 56, 4, p. 1036-1043 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Antiapoptotic effect of highly secreted GMCSF from neuronal cell-specific GMCSF overexpressing neural stem cells in spinal cord injury model

You, Y., Che, L., Lee, H. Y., Lee, H. L., Yun, Y., Lee, M., Oh, J. & Ha, Y., 2015 Jan 1, In : Spine. 40, 24, p. E1284-E1291

Research output: Contribution to journalArticle

6 Scopus citations

Cardiac usage of reducible poly(oligo-D-arginine) as a gene carrier for vascular endothelial growth factor expression

Woo, J., Bae, S. H., Kim, B., Park, J. S., Jung, S., Lee, M., Kim, Y. H. & Choi, D., 2015 Dec 1, In : PLoS ONE. 10, 12, e0144491.

Research output: Contribution to journalArticle

2 Scopus citations

Delivery of anti-microRNA-21 antisense-oligodeoxynucleotide using amphiphilic peptides for glioblastoma gene therapy

Song, H., Oh, B., Choi, M., Oh, J. & Lee, M., 2015 May 1, In : Journal of Drug Targeting. 23, 4, p. 360-370 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Dexamethasone-Conjugated Polyamidoamine Dendrimer for Delivery of the Heme Oxygenase-1 Gene into the Ischemic Brain

Jeon, P., Choi, M., Oh, J. & Lee, M., 2015 Jan 1, In : Macromolecular Bioscience. 15, 7, p. 1021-1028 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Improved islet transplantation outcome by the co-delivery of siRNAs for iNOS and 17β-estradiol using an R3V6 peptide carrier

Hwang, H. J., Lee, M., Park, J. H., Jung, H. S., Kang, J. G., Kim, C. S., Lee, S. J. & Ihm, S. H., 2015 Jan 1, In : Biomaterials. 38, p. 36-42 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Peptide Micelle-Mediated Delivery of Tissue-Specific Suicide Gene and Combined Therapy with Avastin in a Glioblastoma Model

Oh, B., Han, J., Choi, E., Tan, X. & Lee, M., 2015 Apr, In : Journal of Pharmaceutical Sciences. 104, 4, p. 1461-1469 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Reducible Poly(Oligo- d -Arginine) as an Efficient Carrier of the Thymidine Kinase Gene in the Intracranial Glioblastoma Animal Model

Kim, H. A., Lee, H. L., Choi, E., Kim, Y. H. & Lee, M., 2015 Nov 1, In : Journal of Pharmaceutical Sciences. 104, 11, p. 3743-3751 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Thymidine kinase gene delivery using curcumin loaded peptide micelles as a combination therapy for glioblastoma

Hyeong Park, J., Han, J. & Lee, M., 2015 Jan 1, In : Pharmaceutical Research. 32, 2, p. 528-537 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Vascular endothelial growth factor-expressing neural stem cell for the treatment of neuropathic pain

Lee, H. L., Oh, J., Yun, Y., Lee, H. Y., You, Y., Che, L., Lee, M., Kim, K. N. & Ha, Y., 2015 Apr 22, In : NeuroReport. 26, 7, p. 399-404 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Combination of TAT-HMGB1A and R3V6 amphiphilic peptide for plasmid DNA delivery with anti-inflammatory effect

Kim, B., Song, J. H. & Lee, M., 2014 Sep, In : Journal of Drug Targeting. 22, 8, p. 739-747 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combined delivery of BCNU and VEGF siRNA using amphiphilic peptides for glioblastoma

Yi, N., Oh, B., Kim, H. A. & Lee, M., 2014 Feb 1, In : Journal of Drug Targeting. 22, 2, p. 156-164 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Combined delivery of HMGB-1 box A peptide and S1PLyase siRNA in animal models of acute lung injury

Oh, B. & Lee, M., 2014 Feb 10, In : Journal of Controlled Release. 175, 1, p. 25-35 11 p.

Research output: Contribution to journalArticle

36 Scopus citations

Cross-linked iron oxide nanoparticles for therapeutic engineering and in vivo monitoring of mesenchymal stem cells in cerebral ischemia model

Park, J. W., Ku, S. H., Moon, H. H., Lee, M., Choi, D., Yang, J., Huh, Y. M., Jeong, J. H., Park, T. G., Mok, H. & Kim, S. H., 2014 Mar, In : Macromolecular Bioscience. 14, 3, p. 380-389 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Delivery of hypoxia and glioma dual-specific suicide gene using dexamethasone conjugated polyethylenimine for glioblastoma-specific gene therapy

Kim, H. A., Park, J. H., Yi, N. & Lee, M., 2014 Mar 3, In : Molecular Pharmaceutics. 11, 3, p. 938-950 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

MSC-based VEGF gene therapy in rat myocardial infarction model using facial amphipathic bile acid-conjugated polyethyleneimine

Moon, H. H., Joo, M. K., Mok, H., Lee, M., Hwang, K. C., Kim, S. W., Jeong, J. H., Choi, D. & Kim, S. H., 2014 Feb 1, In : Biomaterials. 35, 5, p. 1744-1754 11 p.

Research output: Contribution to journalArticle

56 Scopus citations