• 2324 Citations
  • 19 h-Index
19952019
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Stem cells Chemical Compounds
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Spermatozoa Medicine & Life Sciences
Embryonic Stem Cells Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Pluripotent Stem Cells Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1995 2019

CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis

Poondla, N., Chandrasekaran, A. P., Heese, K., Kim, K-S. & Suresh, R., 2019 Apr 23, In : Biochemical and Biophysical Research Communications. 512, 1, p. 60-65 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
HeLa Cells
Up-Regulation
Down-Regulation
Apoptosis

Deubiquitinating enzymes as cancer biomarkers: new therapeutic opportunities?

Poondla, N., Chandrasekaran, A. P., Kim, K-S. & Suresh, R., 2019 Mar 1, In : BMB reports. 52, 3, p. 181-189 9 p.

Research output: Contribution to journalComment/debateResearch

Tumor Biomarkers
Peptide Hydrolases
Enzymes
Gene therapy
Neoplasms

The stability and oncogenic function of LIN28A are regulated by USP28

Haq, S., Das, S., Kim, D. H., Chandrasekaran, A. P., Hong, S. H., Kim, K-S. & Suresh, R., 2019 Mar 1, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 3, p. 599-610 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Ubiquitin-Specific Proteases
Protein Stability
Ubiquitination
Neoplasms
Proteins
7 Citations (Scopus)

Deubiquitinating enzymes in cancer stem cells: functions and targeted inhibition for cancer therapy

Kaushal, K., Antao, A. M., Kim, K-S. & Suresh, R., 2018 Dec 1, In : Drug Discovery Today. 23, 12, p. 1974-1982 9 p.

Research output: Contribution to journalReview articleResearchpeer-review

Neoplastic Stem Cells
Neoplasms
Stem Cell Factor
Ubiquitination
Therapeutics
1 Citation (Scopus)

Different Methods of Delivering CRISPR/Cas9 Into Cells

Chandrasekaran, A. P., Song, M., Kim, K-S. & Suresh, R., 2018 Jan 1, Progress in Molecular Biology and Translational Science. Teplow, D. B. (ed.). Elsevier B.V., p. 157-176 20 p. (Progress in Molecular Biology and Translational Science; vol. 159).

Research output: Chapter in Book/Report/Conference proceedingChapterResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Guide RNA
Ribonucleoproteins
Plasmids
Molecular Medicine