• 3354 Citations
  • 28 h-Index
1993 …2020

Research output per year

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Research Output

  • 3354 Citations
  • 28 h-Index
  • 89 Article
  • 2 Comment/debate
  • 1 Short survey
2020

Silencing of CD133 inhibits GLUT1-mediated glucose transport through downregulation of the HER3/Akt/mTOR pathway in colon cancer

Kim, H., Ju, J. H., Son, S. & Shin, I., 2020 Mar 1, In : FEBS Letters. 594, 6, p. 1021-1035 15 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Correction to: ECM1 regulates cell proliferation and trastuzumab resistance through activation of EGF-signaling (Breast Cancer Research (2014) 16:6 (479-495) DOI: 10.1186/s13058-014-0479-6)

Lee, K. M., Nam, K., Oh, S., Lim, J., Kim, Y. P., Lee, J. W., Yu, J. H., Ahn, S. H., Kim, S. B., Noh, D. Y., Lee, T. & Shin, I., 2019 Mar 26, In : Breast Cancer Research. 21, 1, 45.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Titanium dioxide nanoparticles induce apoptosis by interfering with EGFR signaling in human breast cancer cells

Kim, H., Jeon, D., Oh, S., Nam, K. S., Son, S., Chan Gye, M. & Shin, I., 2019 Aug, In : Environmental research. 175, p. 117-123 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Toxicological assessment of phthalates and their alternatives using human keratinocytes

Kim, H., Nam, K. S., Oh, S., Son, S., Jeon, D., Chan Gye, M. & Shin, I., 2019 Aug, In : Environmental research. 175, p. 316-322 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Comparative toxicological evaluation of nonylphenol and nonylphenol polyethoxylates using human keratinocytes

Kim, H., Oh, S., Gye, M. C. & Shin, I., 2018 Oct 2, In : Drug and Chemical Toxicology. 41, 4, p. 486-491 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cytotoxicity measurement of Bisphenol A (BPA) and its substitutes using human keratinocytes

Son, S., Nam, K. S., Kim, H., Gye, M. C. & Shin, I., 2018 Jul, In : Environmental research. 164, p. 655-659 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Egr-1 is required for neu/HER2-induced mammary tumors

Oh, S., Kim, H., Nam, K. S. & Shin, I., 2018 May, In : Cellular Signalling. 45, p. 102-109 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Role of the CCN protein family in cancer

Kim, H., Son, S. & Shin, I., 2018 Oct 1, In : BMB reports. 51, 10, p. 486-492 7 p.

Research output: Contribution to journalShort survey

5 Scopus citations
2017

Cytotoxic effect of nano-SiO2 in human breast cancer cells via modulation of EGFR signaling cascades

Jeon, D., Kim, H., Nam, K., Oh, S., Son, S. H. & Shin, I., 2017 Nov, In : Anticancer Research. 37, 11, p. 6189-6197 9 p.

Research output: Contribution to journalArticle

4 Scopus citations
46 Scopus citations

Silencing of Glut1 induces chemoresistance via modulation of Akt/GSK-3β/β-catenin/survivin signaling pathway in breast cancer cells

Oh, S., Kim, H., Nam, K. S. & Shin, I., 2017 Dec 15, In : Archives of Biochemistry and Biophysics. 636, p. 110-122 13 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016

Ablation of CD44 induces glycolysis-To-oxidative phosphorylation transition via modulation of the c-Src-Akt-LKB1-AMPKα pathway

Nam, K. S., Sunhwa, O. H. & Shin, I., 2016 Jan 1, In : Biochemical Journal. 473, 19, p. 3013-3030 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

Elevated STC-1 augments the invasiveness of triple-negative breast cancer cells through activation of the JNK/c-Jun signaling pathway

Han, J., Jeon, M., Shin, I. & Kim, S., 2016 Sep, In : Oncology Reports. 36, 3, p. 1764-1771 8 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

CD44 regulates cell proliferation, migration, and invasion via modulation of c-Src transcription in human breast cancer cells

Nam, K. S., Oh, S., Lee, K. M., Yoo, S. A. & Shin, I., 2015 Sep 1, In : Cellular Signalling. 27, 9, p. 1882-1894 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

Cytokeratin19 induced by HER2ERK binds and stabilizes HER2 on cell membranes

Ju, J. H., Oh, S., Lee, K. M., Yang, W., Nam, K. S., Moon, H. G., Noh, D. Y., Kim, C. G., Park, G., Park, J. B., Lee, T., Arteaga, C. L. & Shin, I., 2015 Apr 4, In : Cell Death and Differentiation. 22, 4, p. 665-676 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

ECM1 promotes the Warburg effect through EGF-mediated activation of PKM2

Lee, K. M., Nam, K., Oh, S., Lim, J., Lee, T. & Shin, I., 2015 Feb 1, In : Cellular Signalling. 27, 2, p. 228-235 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

ECM1 regulates tumor metastasis and CSC-like property through stabilization of β-catenin

Lee, K. M., Nam, K., Oh, S., Lim, J., Kim, R. K., Shim, D., Choi, J. H., Lee, S. J., Yu, J. H., Lee, J. W., Ahn, S. H. & Shin, I., 2015 Dec 10, In : Oncogene. 34, 50, p. 6055-6065 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

EGFR negates the proliferative effect of oncogenic HER2 in MDA-MB-231 cells

Oh, S., Ju, J. H., Yang, W., Lee, K. M., Nam, K. S. & Shin, I., 2015 Jun 1, In : Archives of Biochemistry and Biophysics. 575, p. 69-76 8 p., 6971.

Research output: Contribution to journalArticle

4 Scopus citations

Induction of fibronectin by HER2 overexpression triggers adhesion and invasion of breast cancer cells

Jeon, M., Lee, J., Nam, S. J., Shin, I., Lee, J. E. & Kim, S., 2015 Apr 10, In : Experimental Cell Research. 333, 1, p. 116-126 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

TGFβ1 protects cells from γ-IR by enhancing the activity of the NHEJ repair pathway

Kim, M. R., Lee, J., An, Y. S., Jin, Y. B., Park, I. C., Chung, E., Shin, I., Barcellos-Hoff, M. H. & Yi, J. Y., 2015 Feb 1, In : Molecular Cancer Research. 13, 2, p. 319-329 11 p.

Research output: Contribution to journalArticle

23 Scopus citations
2014

CD24 regulates stemness and the epithelial to mesenchymal transition through modulation of Notch1 mRNA stability by p38MAPK

Lim, J., Lee, K. M., Shim, J. & Shin, I., 2014 Sep 15, In : Archives of Biochemistry and Biophysics. 558, p. 120-126 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling

Lee, K. M., Nam, K., Oh, S., Lim, J., Kim, Y. P., Lee, W. W., Yu, J. H., Ahn, S. H., Kim, S. B., Noh, D. Y., Lee, T. & Shin, I., 2014 Dec 11, In : Breast Cancer Research. 16, 1, 479.

Research output: Contribution to journalArticle

28 Scopus citations

S100A4 negatively regulates β-catenin by inducing the Egr-1-PTEN-Akt-GSK3β degradation pathway

Yang, W., Nam, K. S., Ju, J. H., Lee, K. M., Oh, S. & Shin, I., 2014 Oct, In : Cellular Signalling. 26, 10, p. 2096-2106 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2013

HER2 stabilizes survivin while concomitantly down-regulating survivin gene transcription by suppressing Notch cleavage

Ju, J. H., Yang, W., Oh, S., Nam, K. S., Lee, K. M., Noh, D. Y. & Shin, I., 2013 Apr 1, In : Biochemical Journal. 451, 1, p. 123-134 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Protein kinase B/Akt1 inhibits autophagy by down-regulating UVRAG expression

Yang, W., Ju, J. H., Lee, K. M., Nam, K. S., Oh, S. & Shin, I., 2013 Feb 1, In : Experimental Cell Research. 319, 3, p. 122-133 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells

Ju, J. H., Yang, W., Lee, K. M., Oh, S., Nam, K., Shim, S., Shin, S. Y., Gye, M. C., Chu, I. S. & Shin, I., 2013 Aug 15, In : Clinical Cancer Research. 19, 16, p. 4335-4346 12 p.

Research output: Contribution to journalArticle

33 Scopus citations
2012

Absence of a human DnaJ protein hTid-1S correlates with aberrant actin cytoskeleton organization in lesional psoriatic skin

Choi, J. H., Choi, D. K., Sohn, K. C., Kwak, S. S., Suk, J., Lim, J. S., Shin, I., Kim, S. W., Lee, J. H. & Joe, C. O., 2012 Jul 27, In : Journal of Biological Chemistry. 287, 31, p. 25954-25963 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

A functional comparison between the HER2high/HER3 and the HER2low/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells

Kim, S., Han, J., Shin, I., Kil, W. H., Lee, J. E. & Nam, S. J., 2012 Aug 31, In : Experimental and Molecular Medicine. 44, 8, p. 473-482 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells

Seo, H. S., Choi, H. S., Kim, S. R., Choi, Y. K., Woo, S. M., Shin, I., Woo, J. K., Park, S. Y., Shin, Y. C. & Ko, S. K., 2012 Jul, In : Molecular and Cellular Biochemistry. 366, 1-2, p. 319-334 16 p.

Research output: Contribution to journalArticle

58 Scopus citations

CD24 regulates cell proliferation and transforming growth factor β-induced epithelial to mesenchymal transition through modulation of integrin β1 stability

Lee, K. M., Ju, J. H., Jang, K., Yang, W., Yi, J. Y., Noh, D. Y. & Shin, I., 2012 Nov 1, In : Cellular Signalling. 24, 11, p. 2132-2142 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Down-regulation of estrogen receptor α (ERα) transcriptional activity by p27 is mediated by inhibition of ERα nuclear localization and modulation of the ERα transcriptional complex

Jeon, M. J., Yang, W., Seo, H. S., Wang, E. S. & Shin, I., 2012 Dec 1, In : Cellular Signalling. 24, 12, p. 2249-2258 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Erratum: Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells (Molecular and Cellular Biochemistry DOI: 10.1007/s11010-012-1310-2)

Seo, H. S., Choi, H. S., Kim, S. R., Choi, Y. K., Woo, S. M., Shin, I., Woo, J. K., Park, S. Y., Shin, Y. C. & Ko, S. G., 2012 Sep 1, In : Molecular and Cellular Biochemistry. 368, 1-2, 1 p.

Research output: Contribution to journalComment/debate

19 Scopus citations

Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

Moon, H. G., Yi, J. K., Kim, H. S., Lee, H. Y., Lee, K. M., Yi, M., Ahn, S., Shin, H. C., Ju, J. H., Shin, I., Han, W. & Noh, D. Y., 2012 Dec 10, In : BMC Cancer. 12, 585.

Research output: Contribution to journalArticle

6 Scopus citations

Protein kinase Cδ negatively regulates Notch1-dependent transcription via a kinase-independent mechanism in vitro

Kim, M., Ju, J. H., Jang, K., Oh, S., Song, J., Kim, C. G. & Shin, I., 2012 Feb 1, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1823, 2, p. 387-397 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

The CD49d +/high subpopulation from isolated human breast sarcoma spheres possesses tumor-initiating ability

Lee, K. M., Han, W., Kim, J. B., Shin, I., Ko, E., Park, I. A., Lee, D. S., Oh, K. & Noh, D. Y., 2012 Mar 1, In : International Journal of Oncology. 40, 3, p. 665-672 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
2011

Akt isoform-specific inhibition of MDA-MB-231 cell proliferation

Yang, W., Ju, J. H., Lee, K. M. & Shin, I., 2011 Jan 1, In : Cellular Signalling. 23, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

CD24 enhances DNA damage-induced apoptosis by modulating NF-κB signaling in CD44-expressing breast cancer cells

Ju, J. H., Jang, K., Lee, K. M., Kim, M., Kim, J., Yi, J. Y., Noh, D. Y. & Shin, I., 2011 Oct 1, In : Carcinogenesis. 32, 10, p. 1474-1483 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Induction of apoptotic cell death by Pharbitis nil extract in HER2-overexpressing MCF-7 cells

Ju, J. H., Jeon, M. J., Yang, W., Lee, K. M., Seo, H. S. & Shin, I., 2011 Jan 7, In : Journal of Ethnopharmacology. 133, 1, p. 126-131 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
52 Scopus citations
2010

12-O-Tetradecanoyl phorbol-13-acetate (TPA)-induced growth arrest is increased by silibinin by the down-regulation of cyclin B1 and cdc2 and the up-regulation of p21 expression in MDA-MB231 human breast cancer cells

Kim, S., Lee, H. S., Lee, S. K., Kim, S. H., Hur, S. M., Kim, J. S., Kim, J. H., Choe, J. H., Shin, I., Yang, J. H., Lee, J. E. & Nam, S. J., 2010 Dec 1, In : Phytomedicine. 17, 14, p. 1127-1132 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

A rapid and simple fabrication method for 3-dimensional circular microfluidic channel using metal wire removal process

Song, S. H., Lee, C. K., Kim, T. J., Shin, I. C., Jun, S. C. & Jung, H. I., 2010 Aug, In : Microfluidics and Nanofluidics. 9, 2-3, p. 533-540 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Corepressor MMTR/DMAP1 is an intrinsic negative regulator of CAK kinase to regulate cell cycle progression

Shin, J. H., Kang, H. C., Park, Y. Y., Ha, D. H., Choi, Y. H., Eum, H. Y., Kang, B. G., Chae, J. H., Shin, I., Lee, J. H. & Kim, C. G., 2010 Nov 5, In : Biochemical and Biophysical Research Communications. 402, 1, p. 110-115 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Danshen (Salvia miltiorrhiza) extract inhibits proliferation of breast cancer cells via modulation of akt activity and p27 level

Yang, W., Ju, J. H., Jeon, M. J., Han, X. & Shin, I., 2010 Feb 1, In : Phytotherapy Research. 24, 2, p. 198-204 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Effects of endocrine disruptors on bombina orientalis P450 aromatase activity

Lee, K. M., Yang, W., Rhee, J. S., Hwang, D. S., Jin Park, C., Gye, M. C., Lee, J. S. & Shin, I., 2010 Apr 1, In : Zoological Science. 27, 4, p. 338-343 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pifithrin-α, an inhibitor of p53 transactivation, up-regulates COX-2 expression through an MAPK-dependent pathway

Kim, S., Han, J., Lee, S. K., Hur, S. M., Koo, M., Cho, D. H., Bae, S. Y., Choi, M. Y., Shin, I., Yang, J. H., Nam, S. J. & Lee, J. E., 2010 Dec 1, In : Pharmacology. 86, 5-6, p. 313-319 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Protein expression profiling of primary mammary epithelial cells derived from MMTV-neu Mice Revealed that HER2/NEU-driven changes in protein expression are functionally clustered

Park, S., Lee, K. M., Ju, J. H., Kim, J., Noh, D. Y., Lee, T. & Shin, I., 2010, In : IUBMB Life. 62, 1, p. 41-50 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation

Jang, K., Kim, M., Seo, H. S. & Shin, I., 2010 Sep 1, In : Oncology Reports. 24, 3, p. 787-793 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

The alkaloid Berberine inhibits the growth of Anoikis-resistant MCF-7 and MDA-MB-231 breast cancer cell lines by inducing cell cycle arrest

Kim, J. B., Yu, J. H., Ko, E., Lee, K. W., Song, A. K., Park, S. Y., Shin, I., Han, W. & Noh, D. Y., 2010 May 1, In : Phytomedicine. 17, 6, p. 436-440 5 p.

Research output: Contribution to journalArticle

80 Scopus citations
2009

Effect of p27 on motility of MDA-MB-231 breast cancer cells

Lee, E. Y., Jeon, M. J., Yang, W. & Shin, I., 2009 Aug 12, In : Oncology Reports. 21, 6, p. 1621-1625 5 p.

Research output: Contribution to journalArticle

3 Scopus citations